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Perspective バックナンバー 2003年
| (16 December 2003) | |
| パートナー探し： シグナル伝達ネットワークに応用された新興のタンパク質相互作用技術 Finding Partners: Emerging Protein Interaction Technologies Applied to Signaling Networks Igor Stagljar* Sci. STKE, Vol. 2003, Issue 213, pp. pe56, 16 December 2003 [DOI: 10.1126/stke.2132003pe56] |
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| ［日本語要約］［英文原文］ | |
| (02 December 2003) | |
| 微小伝達物質放出：自然界の偶然か慎重な設計か？ Miniature Transmitter Release: Accident of Nature or Careful Design? Yo Otsu1,2 and Timothy H. Murphy1,2,3* Sci. STKE, Vol. 2003, Issue 211, pp. pe54, 2 December 2003 [DOI: 10.1126/stke.2003.211.pe54] |
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| ［日本語要約］［英文原文］ | |
| (11 November 2003) | |
| 変異型TNF分子のコンピューターデザイン：炎症促進カスケード阻害の新規な方法論 Computational Design of Variant TNF Molecules: A Novel Methodology for Inhibition of Proinflammatory Cascades Edward Abraham* Sci. STKE, Vol. 2003, Issue 208, pp. pe51, 11 November 2003 [DOI: 10.1126/stke.2003.208.pe51] |
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| ［日本語要約］［英文原文］ | |
| (04 November 2003) | |
| ハンチンチン：活発かつ元気に中間管理で作用する Huntingtin: Alive and Well and Working in Middle Management Marcy E. MacDonald* Sci. STKE, Vol. 2003, Issue 207, pp. pe48, 4 November 2003 [DOI: 10.1126/stke.2003.207.pe48] |
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| ［日本語要約］［英文原文］ | |
| 精神疾患におけるシグナル伝達および遺伝子から行動への経路 Signal Transduction and Genes-to-Behaviors Pathways in Psychiatric Diseases Husseini K. Manji1*, Irving I. Gottesman2*, and Todd D. Gould1* Sci. STKE, Vol. 2003, Issue 207, pp. pe49, 4 November 2003 [DOI: 10.1126/stke.2003.207.pe49] |
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| ［日本語要約］［英文原文］ | |
| 神経伝達物質トランスポーターに狙いを定めたシグナル伝達経路 Signaling Pathways Take Aim at Neurotransmitter Transporters Michael B. Robinson* Sci. STKE, Vol. 2003, Issue 207, pp. pe50, 4 November 2003 [DOI: 10.1126/stke.2003.207.pe50] |
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| ［日本語要約］［英文原文］ | |
| (28 October 2003) | |
| 薬物発見におけるマイクロアレイ分析：うつ病の希望を与える展望 Microarray Analysis in Drug Discovery: An Uplifting View of Depression Shawn E. Levy* Sci. STKE, Vol. 2003, Issue 206, pp. pe46, 28 October 2003 [DOI: 10.1126/stke.2003.206.pe46] |
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| ［日本語要約］［英文原文］ | |
| アンチセンス核酸分子の治療効果の可能性 Therapeutic Potential of Antisense Nucleic Acid Molecules Joanna B. Opalinska1* and Alan M. Gewirtz2* Sci. STKE, Vol. 2003, Issue 206, pp. pe47, 28 October 2003 [DOI: 10.1126/stke.2003.206.pe47] |
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| ［日本語要約］［英文原文］ | |
| (21 October 2003) | |
| リーリンは神経筋接合部におけるシナプス除去に対する答えか？ Is Reelin the Answer to Synapse Elimination at the Neuromuscular Junction? Ben Chih and Peter Scheiffele* Sci. STKE, Vol. 2003, Issue 205, pp. pe45, 21 October 2003 [DOI: 10.1126/stke.2003.205.pe45] |
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| ［日本語要約］［英文原文］ | |
| (14 October 2003) | |
| 光受容器の明順応におけるタンパク質移行：脊椎動物と無脊椎動物の視覚における共通テーマ Protein Translocation in Photoreceptor Light Adaptation: A Common Theme in Vertebrate and Invertebrate Vision Vadim Y. Arshavsky* Sci. STKE, Vol. 2003, Issue 204, pp. pe43, 14 October 2003 [DOI: 10.1126/stke.2003.204.pe43] |
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| ［日本語要約］［英文原文］ | |
| PDE4：境界で捕まる PDE4: Arrested at the Border Laurence L. Brunton* Sci. STKE, Vol. 2003, Issue 204, pp. pe44, 14 October 2003 [DOI: 10.1126/stke.2003.204.pe44] |
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| ［日本語要約］［英文原文］ | |
| (07 October 2003) | |
| ついに大量破壊兵器の証拠が得られた Finally, Proof of Weapons of Mass Destruction Ian T. Baldwin* Sci. STKE, Vol. 2003, Issue 203, pp. pe42, 7 October 2003 [DOI: 10.1126/stke.2003.203.pe42] |
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| ［日本語要約］［英文原文］ | |
| (30 September 2003) | |
| 選択は分子ネットワークを形作るか？ Does Selection Mold Molecular Networks? Andreas Wagner* Sci. STKE, Vol. 2003, Issue 202, pp. pe41, 30 September 2003 [DOI: 10.1126/stke.2003.202.pe41] |
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| ［日本語要約］［英文原文］ | |
| (23 September 2003) | |
| 死神の裏をかく（OutFOXing the Grim Reaper）：フォークヘッド転写因子による長寿を制御する新規機構 OutFOXing the Grim Reaper: Novel Mechanisms Regulating Longevity by Forkhead Transcription Factors Paul Coffer* Sci. STKE, Vol. 2003, Issue 201, pp. pe39, 23 September 2003 [DOI: 10.1126/stke.2003.201.pe39] |
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| ［日本語要約］［英文原文］ | |
| サイトカイン受容体gp130 忠実な不規則性 The Cytokine Receptor gp130: Faithfully Promiscuous Gerhard Muller-Newen* Sci. STKE, Vol. 2003, Issue 201, pp. pe40, 23 September 2003 [DOI: 10.1126/stke.2003.201.pe40] |
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| ［日本語要約］［英文原文］ | |
| (16 September 2003) | |
| 依存性受容体（Dependence Receptors）：どんなメカニズムか？ Dependence Receptors: What Is the Mechanism? Moses V. Chao* Sci. STKE, Vol. 2003, Issue 200, pp. pe38, 16 September 2003 [DOI: 10.1126/stke.2003.200.pe38] |
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| ［日本語要約］［英文原文］ | |
| (9 September 2003) | |
| いかだと流水（膜微小ドメインと浸透圧） Of Rafts and Moving Water David M. Cohen* Sci. STKE, Vol. 2003, Issue 199, pp. pe36, 9 September 2003 [DOI: 10.1126/stke.2003.199.pe36] |
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| ［日本語要約］［英文原文］ | |
| Erbin：ErbB2受容体を選別するのか、それともRasを阻害するのか？ Erbin: Sorting Out ErbB2 Receptors or Giving Ras a Break? Walter Kolch* Sci. STKE, Vol. 2003, Issue 199, pp. pe37, 9 September 2003 [DOI: 10.1126/stke.2003.199.pe37] |
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| ［日本語要約］［英文原文］ | |
| (19 August 2003) | |
| 組織化された生命活動：細胞表面から基底膜まで Organized Living: From Cell Surfaces to Basement Membranes Nancy J. Boudreau* Sci. STKE, Vol. 2003, Issue 196, pp. pe34, 19 August 2003 [DOI: 10.1126/stke.2003.196.pe34] |
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| ［日本語要約］［英文原文］ | |
| n vivoの正常状態で受容体に依存せずにヘテロ三量体G蛋白質が活性化される証拠： 線虫における紡錘体の位置決め Evidence Mounts for Receptor-Independent Activation of Heterotrimeric G Proteins Normally in Vivo: Positioning of the Mitotic Spindle in C. Elegans David R. Manning* Sci. STKE, Vol. 2003, Issue 196, pp. pe35, 19 August 2003 [DOI: 10.1126/stke.2003.196.pe35] |
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| ［日本語要約］［英文原文］ | |
| (12 August 2003) | |
| MSK1・MSK2を介したヒストンH3の増殖因子刺激誘発性およびストレス誘発性リン酸化： 論争の決着 MSK1 and MSK2 Mediate Mitogen- and Stress-Induced Phosphorylation of Histone H3: A Controversy Resolved James R. Davie* Sci. STKE, Vol. 2003, Issue 195, pp. pe33, 12 August 2003 [DOI: 10.1126/stke.2003.195.pe33] |
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| ［日本語要約］［英文原文］ | |
| (05 August 2003) | |
| GβγとKACh：よくある話、新しい洞察（Old Story,
New Insights ） GβγとKACh: Old Story, New Insights Tooraj Mirshahi, Taihao Jin, and Diomedes E. Logothetis* Sci. STKE, Vol. 2003, Issue 194, pp. pe32, 5 August 2003 [DOI: 10.1126/stke.2003.194.pe32] |
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| ［日本語要約］［英文原文］ | |
| (29 July 2003) | |
| アポトーシス誘導因子（AIF）： 「生と死」機構の多機能性の歯車 AIF: A Multifunctional Cog in the Life and Death Machine Tania M. Hansen* and Phillip Nagley* Sci. STKE, Vol. 2003, Issue 193, pp. pe31, 29 July 2003 [DOI: 10.1126/stke.2003.193.pe31] |
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| ［日本語要約］［英文原文］ | |
| (22 July 2003) | |
| T細胞−樹状細胞のin vivo相互作用：不規則な接触は長期的な連携の発達を促進する T Cell-Dendritic Cell Interaction in Vivo: Random Encounters Favor Development of Long-Lasting Ties Oreste Acuto Sci. STKE, Vol. 2003, Issue 192, pp. pe28, 22 July 2003 [DOI: 10.1126/stke.2003.192.pe28] |
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| ［日本語要約］［英文原文］ | |
| 哺乳類では、メラトニン分泌パターンを介して母親から胎児へ光周期情報が伝達される Pattern of Melatonin Secretion Mediates Transfer of Photoperiod Information from Mother to Fetus in Mammals Bruce D. Goldman Sci. STKE, Vol. 2003, Issue 192, pp. pe29, 22 July 2003 [DOI: 10.1126/stke.2003.192.pe29] |
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| ［日本語要約］［英文原文］ | |
| ヘッジホッグシグナル伝達の現在利用されている干渉 Running Interference for Hedgehog Signaling Alan M. Michelson Sci. STKE, Vol. 2003, Issue 192, pp. pe30, 22 July 2003 [DOI: 10.1126/stke.2003.192.pe30] |
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| ［日本語要約］［英文原文］ | |
| (15 July 2003) | |
| Gβ構造の模倣物として役割を果たすKelch βプロペラ構造：車輪の再発明？ A Kelch β Propeller Featuring as a Gβ Structural Mimic: Reinventing the Wheel? Jan Gettemans*, Kris Meerschaert, Joel Vandekerckhove, and Veerle De Corte Sci. STKE, Vol. 2003, Issue 191, pp. pe27, 15 July 2003 [DOI: 10.1126/stke.2003.191.pe27] |
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| ［日本語要約］［英文原文］ | |
| (08 July 2003) | |
| お似合いの修飾タンパク質 Matching Accessories Steven M. Foord Sci. STKE, Vol. 2003, Issue 190, pp. pe25, 8 July 2003 [DOI: 10.1126/stke.2003.190.pe25] |
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| ［日本語要約］［英文原文］ | |
| ユビキチン化、タンパク質代謝回転、長期的シナプス可塑性 Ubiquitination, Protein Turnover, and Long-Term Synaptic Plasticity James H. Schwartz Sci. STKE, Vol. 2003, Issue 190, pp. pe26, 8 July 2003[DOI: 10.1126/stke.2003.190.pe26] |
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| ［日本語要約］［英文原文］ | |
| (01 July 2003) | |
| 年老いた犬と新しい芸、プロテアーゼ、阻害剤、および細胞遊走 Old Dogs and New Tricks, Proteases, Inhibitors, and Cell Migration Steingrimur Stefansson and Daniel A. Lawrence Sci. STKE, Vol. 2003, Issue 189, pp. pe24, 1 July 2003 [DOI: 10.1126/stke.2003.189.pe24] |
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| ［日本語要約］［英文原文］ | |
| (24 June 2003) | |
| CICチャネルでは、イオン透過とゲーティングが連結している Coupling Gating with Ion Permeation in ClC Channels Tsung-Yu Chen Sci. STKE, Vol. 2003, Issue 188, pp. pe23, 24 June 2003 [DOI: 10.1126/stke.2003.188.pe23] |
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| ［日本語要約］［英文原文］ | |
| (3 June 2003) | |
| サブオペロンによる制御シグナル Suboperonic Regulatory Signals Sankar Adhya Sci. STKE, Vol. 2003, Issue 185, pp. pe22, 3 June 2003 [DOI: 10.1126/stke.2003.185.pe22] |
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| ［日本語要約］［英文原文］ | |
| (27 May 2003) | |
| B細胞シグナル伝達のアイソタイプによる制御 Isotype Control of B Cell Signaling Karlee Silver and Richard J. Cornal Sci. STKE, Vol. 2003, Issue 184, pp. pe21, 27 May 2003 [DOI: 10.1126/stke.2003.184.pe21] |
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| ［日本語要約］［英文原文］ | |
| (20 May 2003) | |
| 糸状仮足は成長円錐に進路を見つけさせることができるのだろうか？ Do Filopodia Enable the Growth Cone to Find Its Way? Anthony J. Koleske Sci. STKE, Vol. 2003, Issue 183, pp. pe20, 20 May 2003 [DOI: 10.1126/stke.2003.183.pe20] |
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| ［日本語要約］［英文原文］ | |
| (13 May 2003) | |
| 一酸化窒素シグナルトランスデューサーとしての鉄調節タンパク質 Iron Regulatory Proteins as NO Signal Transducers Cecile Bouton and Jean-Claude Drapier Sci. STKE, Vol. 2003, Issue 182, pp. pe17, 13 May 2003 [DOI: 10.1126/stke.2003.182.pe17] |
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| ［日本語要約］［英文原文］ | |
| 亜鉛の画像化：昔の道具と新しい機器 Imaging Zinc: Old and New Tools Christopher Frederickson Sci. STKE, Vol. 2003, Issue 182, pp. pe18, 13 May 2003 [DOI: 10.1126/stke.2003.182.pe18] |
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| ［日本語要約］［英文原文］ | |
| われわれは考えるとき亜鉛が必要なのだろうか？ Do We Need Zinc to Think? Yang V. Li, Christopher J. Hough, and John M. Sarvey Sci. STKE, Vol. 2003, Issue 182, pp. pe19, 13 May 2003 [DOI: 10.1126/stke.2003.182.pe19] |
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| ［日本語要約］［英文原文］ | |
| (6 May 2003) | |
| アンジオテンシン2型受容体（AT2R）：魅力的な双子の片方 Angiotensin Type 2 Receptor (AT2R): A Challenging Twin Bradford C. Berk Sci. STKE, Vol. 2003, Issue 181, pp. pe16, 6 May 2003 [DOI: 10.1126/stke.2003.181.pe16] |
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| ［日本語要約］［英文原文］ | |
