Anti RNA polymerase 2, CTD Ser5ph - Cosmo Bio Co.,Ltd.



Anti RNA polymerase 2, CTD Ser5ph Antibody

Catalog No.: CAC-CE-031A
Size: 100UL
[1 mg / mL]
Price: ¥58000
antigen/source: RNA polymerase 2, CTD Ser5ph
host: Rat
Label: Unlabeled
Purity: Ig fraction - Ion Exchange /Gel Filtration
Application: Western Blot
Immunocytochemistry (cell)
Chromatin Immunoprecipitation
Storage: -70C
Isotype: IgG2b
Clone: 1H4B6
Reacts with: Human


RNA polymerase II (RNAPII) transcribes all protein-coding genes and many non-coding genes, and the activity of RNAPII correlates with the phosphorylation state of RPB1, the large catalytic subunit of RNAPII.. RPB1 has an unusual C-terminal domain (CTD) that consists of repeats of the heptapeptide consensus sequence N-Tyr1-Ser2-Pro3-Thr4-Ser5-Pro6-Ser7-C, of which there are 52 copies in mammals. The amino acids in these repeats are potential targets for modification, such as phosphorylation and glycosylation.