Anti 5-Fluorouracil - Cosmo Bio Co.,Ltd.

Antibodies

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Anti 5-Fluorouracil Antibody

Catalog No.: CAC-NM-MA-002
Size: 1VIAL
Price: ¥40000
$534
antigen/source: 5-Fluorouracil (CAS:51-21-8)
host: Mouse
Label: Unlabeled
Purity: Semi Purified
Application: Enzyme Linked Immunosorbent Assay
Storage: -20C
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Clone: H3-17
Shape: Lyophilized
Molecular Weight: 130.08
Purpose: ELISA: 1/1000
Other applications have not been tested.
Optimal dilutions/concentrations should be determined by the end user.

Other:

 Background 
5-Fluorouracil (5-FU) is a pyrimidine analogue and inhibits an enzyme called thymidylate synthetase, which results in inhibition of DNA replication. Thus, 5-FU is used as a drug in the treatment of cancers including colorectal cancer,pancreatic cancer and skin cancer.



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5-Fluorouracil

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Fig.1 Monoclonal antibody (H3-17) shows high binding to 5-FU-BSA but undetectable binding to BSA. Different dilutions of antibody were tested for binding to immobilized antigens (100 ng/well) in a direct ELISA.

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Fig.2 Monoclonal antibody (H3-17) is capable of binding to free 5-FU. Free 5-FU efficiently inhibits the antibody binding to immobilized 5-FU-BSA (5 ng/well), which was detected by a competitive ELISA.

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