Anti EVC - Cosmo Bio Co.,Ltd.

Antibodies

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Anti EVC Antibody

Catalog No.: CAC-OUA-P01-A
Size: 100UL
Price: ¥30000
$400
antigen/source: EVC
host: Rabbit
Label: Unlabeled
Purity: Affinity Purified
Application: Western Blot
Immunohistochemistry
Storage: -20C
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Immunogen: Rat
Isotype: IgG
Reacts with: Rat
Mouse
Shape: Liquid

Other:

 Background 
Ellis-van Creveld syndrome is a hereditary disease characterized by short and small limbs due to chondrodysplasia (1), and Ellis-van Creveld (EVC) was identified as responsible gene (2). EVC retains transmembrane domain, leucine zipper domain and nuclear localization signal. EVC is related to proliferation and differentiation of chondrocyte in bone development. By immunostaining using this antibody, the signals were obtained from chondrocytes in mature layer to hypertrophy layerof growth-platecartilage (3).
 Application 
Western Blot: 1/500-1/1,000 (Predicted molecular weight: 110kDa)
Immunohistochemistry: 1/500-1/1,000
Optimal dilutions/concentrations should be determined by the end user.
Cross reactivity:Rat, Mouse


Reference:

•  Ellis RWB, van Creveld S. 1940. Arch. Dis. Child, 15:65-84.
•  Ruiz-Perez VL, et al.,. 2000. Nat. Genet., 24:283-286.
•  Tsuji, T. et al.,2004 Anatomical Record. Anatomical Record 279A: 729-723.
 
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