Anti Chondroitin Sulfate A - Cosmo Bio Co.,Ltd.

Antibodies

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Anti Chondroitin Sulfate A Antibody

Catalog No.: CAC-NU-07-001
Size: 200UL
[1 mg / mL]
Price: ¥50000
$667
antigen/source: Chondroitin Sulfate A
host: Mouse
Description: Chondroitin sulfate proteoglycans purified from 10-day-old rat brain
Purity: -
Application: Western Blot
Enzyme Linked Immunosorbent Assay
Immunoprecipitation
IHC frozen section
IHC paraffin embedding section
Storage: -20C
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Immunogen: Rat
Isotype: IgM
Clone: 2H6
Reacts with: Rat
Animal
Purpose: Western blotting: 1/10,000
- Immunohistochemistry: 1/100 (Paraffin section), Available (Frozen section)
- Immunoprecipitaion: Available
- ELISA: 1/1,000 ~ 1/2,000
Other applications have not been tested.
Optimal dilutions/concentrations should be determined by the end user.

Other:

[BACKGROUND]
Chondroitin sulfate, a polysaccharide moiety of proteoglycans, is one of the major components of the extracellular matrix of the animal body, and is composed of the repeating unit, [4GlcA 13GalNAc 1], commonly sulfated at the C-4 and/or C-6 of GalNAc. In the central nervous system, the most abundant glycosaminoglycan is chondroitin sulfate rich in [GlcA-GalNAc(4S)], namely chondroitin sulfate A. Chondroitin sulfate polysaccharides are involved in various cellular events inthe formation, regeneration, and maintenance of the neural network. This monoclonal antibody recognizes effectively chondroitin sulfate A, especially the glycosaminoglycan existing in the developing central nervous system.



 IMAGE1



Immunohistochemical staining using the monoclonal anti-chondroitin sulfate A antibody (clone 2H6) Paraffin sections of omasal papilla from the adult sheep were stained with the monoclonal anti-chondroitin sulfate A antibody before (A) and after (B) digestion with chondroitinase ABC. After pretreatment with the enzyme, the immunoreactivity completely disappeared. Reference: Eur. J. Histochem., 39 (1995) 265-272.

Reference:

•  Oohira, A., et al., Neuroscience, 60, 145-157 (1994) PMID: 8052408
◊  Yamamoto, Y., et al.,: Eur. J. Histochem., 39, 265-272 (1995) PMID: 8835180
 
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