Anti gamma-Tubulin (E39) - Cosmo Bio Co.,Ltd.

Antibodies

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Anti gamma-Tubulin (E39) Antibody

Catalog No.: CAC-NM-MA-003
Size: 100UL
Price: ¥40000
$534
antigen/source: Whole length of human gamma-tubulin 1 protein
host: Mouse
Label: Unlabeled
Application: Immunocytochemistry (cell)
Western Blot
Enzyme Linked Immunosorbent Assay
Storage: -20C
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Isotype: IgG1
Clone: E39
Purpose: Immunocytochemistry: 1/200
Western blotting: 1/1000
ELISA: 1/1000
Other applications have not been tested.
Optimal dilutions/concentrations should be determined by the end user.

Other:

 Background 
Gamma-tubulins constitute a ubiquitous and highly conserved subfamily of the tubulin family. The protein is found at microtubule-organising centres, such as the spindle poles or the centrosome. It remains associated with the centrosome when microtubules are depolymerised, suggesting that it is an integral component that might play a role in minus-end nucleation of microtubule assembly. Thus, gamma-tubulins can be used for centrosome maker of the cells.
 Cross reactivity 
Human, Mouse, and Rat



 IMAGE1



Monoclonal antibody (E39) recognizes gamma-tubulin located at the centrosomes. Gamma-tubulin in normal or cancer cells was stained by an immunofluorescence described below. The presence of supernumerary centrosomes is a common event in human tumors. Yellow and blue indicate gamma-tubulin and nuclear DNA, respectively. A; normal human fibroblasts, B; colon cancer cell line (CaCo-2), C; fibrosarcoma cell line (HT-1080).
 
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