Glucagon-Like Peptide 2 EIA - Cosmo Bio Co.,Ltd.

Antibodies

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Glucagon-Like Peptide 2 EIA

Catalog No.: YII-YK141-EX
Size: 1KIT
Price: ¥76000
$1014
antigen/source: GLP-2
catalog info: Catalog 2012-p111
Storage: 4C
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Immunogen: Human
Reacts with: Human
Measurement Range: 0.412-100 ng/mL
Purpose: This EIA kit is highly specific to human GLP-2 and shows crossreactivity to neither glucagon (rat/mouse/human) nor GLP-1 even at a concentration of 300 pmol/mL.
component: Antibody: X
Plate: X
Coating: X
Control: -
Standard: X
Labeling: X
Substrate: X
Others: X
1. Antibody coated plate 1 plate (96 wells)
2. Human GLP-2 standard 1 vial (50 ng)
3. Labeled antigen 1 vial
4. GLP-2 antibody 1 bottle (6 mL )
5. SA-HRP solution 1 bottle (12 mL )
6. Substrate buffer 1 bottle (26 mL )
7. OPD tablet 2 tablets
8. Stopping solution 1 bottle (12 mL )
9. Buffer solution 1 bottle (25 mL )
10. Washing solution 1 bottle (50 mL )
11. Adhesive foil 3 pieces

Other:

 Supplementary 
Competitive
 Applicable sample 
Plasma, Serum
[Other]
Proglucagon gene is expressed in both pancreatic A cell and intestinal L cell. Tissue-specific posttranslational processing of proglucagon by prohormone convertase produces different proglucagon derived peptides (PGDPs) in both pancreas and intestine. The most notable pancreatic PGDP is glucagon, whereas intestinal L cell produces several structurally related peptides, including glucagon-like peptide 1 (GLP-1) and2 (GLP-2), as well as glicentin and oxyntomodulin which contain glucagon sequence in their molecules. Among PGDPs, GLP-2 has been found to show intestinal epithelial proliferation.


Reference:

•  Philippe J. Endocr Rev 12: 252-271,1991
•  Mojsov S. et al., J Biol Chem 261: 11880-11889,1986
•  Drucker D.J. et al., Proc Natl Acad Sci USA 93: 7911-7916,1996
•  Brubaker PL, et al., Endocrinology 15: 673-677,1997
•  Drucker D. J. Diabetes 47: 159-169, 1998
•  Xiao Q, et al., Gastroenterology 117: 99-105,1999
7. Kato I, et al., Peptide Science 1999: N.Fujii(Ed). The Japanese Peptide Society (2000)
•   Cani PD, Possemiers S, Van de Wiele T, Guiot Y, Everard A, Rottier O, Geurts L, Naslain D, Neyrinck A, Lambert DM, Muccioli GG, Delzenne NM. Gut. 2009 Aug;58(8):1091-103.
 
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