Native collagen, Bovine dermis, 5mg/mL - Cosmo Bio Co.,Ltd.

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Native collagen, Bovine dermis, 5mg/mL

Catalog No.: KOU-IAC-50
Size: 50ML
[BOTTLE]
Price: ¥23700
$316
catalog info: Catalog 2012-p276
Storage: 4C DNF
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Purpose: Collagen solutions for cell and tissue culturing

Other:

 Background 
Collagen solution for cell and tissue culturing is highly Purified collagen solution manufactured in KOUKEN (Tokyo) advanced technology with excellent quality control.
Cell and tissue cultures with Koken collagen solutions can express cellular functions like in vivo cells. Collagen not only plays the role of physical scaffold for the proliferating cells, but also enhances cell adhesion, proliferation and function. Collagen creates a natural extracellular environment that is important for cell communication and layer formation. The synthesizing capability of albumin, a functions shared among hepatocytes, is maintained at a high level when cultured on plates coated with collagen solution. When skin fibroblasts are culturedthree-dimensionally on collagen gel , the whole collagen contracts from the contractility of the cells producing a dermis model that closely resembles the structure of live dermis.
[Features and Advantages]
1. All products are sterilized. The used collagen are extracted from bovine dermis, solubilized and purified by our original methods.
2. Acidic solutions, I-PC and I-AC, form fibrils when being neutralized at 37C
Application
# Collagen coating of culture plates
# Three dimensional culture in a collagen gel
# Culture on a gel
[Delivery Note]
The product contains bovine collagen. It was supplied from Australia/New Zealand and was certified about its non-hazardous by each quarantine. Please confirm the possibility of importing such bovine related item in your country before order.



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Reference:

•  Narisawa-Saito M, Yoshimatsu Y, Ohno S, et al., Cancer Res. 2008 Jul 15;68(14):5699-705
•  Eguchi R, Naitou H, Kunimasa K, et al., Proteomics. 2008 Jul;8(14):2897-906
•  Hannachi Imen E, Nakamura M, Mie M, Kobatake E. J Biotechnol. 2009 Jan 1;139(1) :19-25
•  Eguchi R, Tone S, Suzuki A, et al., Exp Cell Res. 2009 Jan 15;
 
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