Anti COMP Fragment (2117B2) - Cosmo Bio Co.,Ltd.

Antibodies

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Anti COMP Fragment (2117B2) Antibody

Catalog No.: CAC-PRPG-CPF-M01
Size: 2ML
Price: ¥50000
$667
antigen/source: COMP Fragment
host: Mouse
Label: Unlabeled
Purity: Supernatant
Application: IHC frozen section
Western Blot
Enzyme Linked Immunosorbent Assay
Storage: -20C
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Immunogen: Human
Clone: 2117B2
Reacts with: Human

Other:

 Background :
COMP - Cartilage oligomeric matrix protein - belongs to the thrombospondin family of ECM components and is a prominent multidomain lycoprotein of cartilage, accounting for up to 1% of the wet weight of articular tissues and having an approximate Mr of 97 kDa [1-4]. COMP may also be found in tendon, bone (i.e. osteoblasts), ligament, certain smooth
muscles and synovium and more recently has been discovered to be a primary constituents of the dermal ECM [5]. In the ECM COMP is present in a pentameric, disulfide-bonded complex of an Mr of about 550 kDa, often seen associated with the chondrocyte cell surface [3, 5]..
 Application 
Western blotting, 1/20 - 1/40*
Immunohistochemistry, 1/20 - 1/30 (Paraffin sections)
Optimal dilutions/concentrations should be determined by the end user


Reference:

•  Oldberg A, et al., J Biol Chem. 1992 Nov 5;267(31):22346-50. PMID: 1429587
•  Hedbom E, et al., J Biol Chem. 1992 Mar 25;267(9):6132-6.. PMID: 1556121
•  Morgelin M, et al., J Biol Chem. 1992 Mar 25;267(9):6137-41.PMID: 1556122
•  Cesare PE, et al., J Orthop Res. 1995 May;13(3):422-8.. PMID: 7602403
•  Agarwal P, et al., J Biol Chem. 2012 Jun 29;287(27):22549-59. PMID: 22573329
 
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