Anti Versican (6B10) - Cosmo Bio Co.,Ltd.

Antibodies

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Anti Versican (6B10) Antibody

Catalog No.: CAC-PRPG-VS-M04
Size: 2ML
Price: ¥50000
$667
antigen/source: Versican / CSPG2
host: Mouse
Label: Unlabeled
Purity: Supernatant
Application: Western Blot
Enzyme Linked Immunosorbent Assay
Immunohistochemistry
Storage: -20C
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Immunogen: Human
Isotype: IgG2a
Clone: 6B10
Reacts with: Human
Bovine
Shape: Liquid

Other:

 Background :
Versican, the product of the VCAN/CSPG2 gene, is a large extracellular matrix chondroitin sulfate proteoglycan ubiquitously expressed in interstitial matrices of the human body, including brain ECM [1-4]. It was first isolated from bovine aorta [5, 6] and later on isolated from the chick embryo [7]. Cloning of the human VCAN/CSPG2 gene was accomplished in 1989 by D. Zimmermann and E. Ruoslahti [8], who also cognated the name versican in recognition of its
versatile modular structure.
[Immunogen]:
Versican-enriched proteoglycan preparation from bovine aorta
 Cross reactivity :
Human, Bovine Other species have not been tested
 Application :
E Western blotting, 1/20 - 1/60*
E Immunohistochemistry, 1/20 - 1/40(Paraffin sections)
E ELISA, 1/50 - 1/150

Optimal dilutions/concentrations should be determined by the end user.


Reference:

•  Wight TN., Curr Opin Cell Biol.2002 Oct;14(5):617-23. PMID:12231358
•  Wu YJ, et al., Cell Res. 2005 Jul;15(7):483-94. PMID:16045811.
•  Cattaruzza S, et al., J Biol Chem. 2002 Dec 6;277(49):47626-35..PMID:12221092
•  Garusi E, et al., Cell Mol Life Sci. 2012 Feb;69(4):553-79. PMID:21964924
•  Heinegard D, et al., Biochem J. 1985 Aug 15;230(1):181-94. PMID:4052035
•  Kimata K, et al., J Biol Chem.1986 Oct 15;261(29):13517-25.PMID:3759975
•  Morgelin M., et al., J Biol Chem.1989 Jul 15;264(20):12080-90. PMID:2745430
•  Zimmermann DR, et al., EMBO J. 1989 Oct;8(10):2975-81. PMID:2583089
 
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