Anti NOD1 - Cosmo Bio Co.,Ltd.

Antibodies

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Anti NOD1 Antibody

Catalog No.: CAC-THU-A-NOD1
Size: 50UL
Price: ¥30000
$400
antigen/source: NOD1
host: Rabbit
Label: Unlabeled
Purity: Affinity Purified
Application: Western Blot
Immunohistochemistry
Flow Cytometry
Storage: -20C
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Immunogen: Porcine
Isotype: IgG

Other:

 Background 
A cytosolic surveillance system mediated by the nucleotide-binding oligomerization domain (NOD) proteins plays an important role in recognizing intracellular microbe-associated molecular patterns (MAMPs). It has been found that
meso-diaminopimelic acid (meso-DAP)-containing peptide moieties, such as -D-glutamyl-meso-DAP (iE-DAP) are recognized by NOD1. Porcine NOD1 is more closely related to the human protein than the mouse counterpart and that it is expressed not only in the cytoplasm but also on the inner side of the plasma membrane in the transfected cells. This antibody is useful for biochemical and immunohistochemical analyzes of porcine NOD1 and for clarifying how the
immune system is modulated by low-molecular weight peptidoglycan fragments through NOD1.
[Product type]: Primary antibody
[Immunogen]: Amino acids 404-416 of porcine NOD1
[Rased in]: Rabbit
 Cross reactivity :
Reacts with porcine. Not yet tested in other species
[Application notes Recommended dilutions]
E Immunohistochemistry: 1/25-1/500
E Flow cytometry: 1/50-1/500
E Western blotting: 1/25-1/500
Other applications have not been tested.
Optimal dilutions/concentrations should be determined by the end user.



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Reference:

•  Tohno M, Shimazu T, Aso H, Uehara A, Takada H, Kawasaki A, Fujimoto Y, Fukase K, Saito T, Kitazawa H., Mol Immunol. 2008 Mar;45(6):1807-17. PMID: 17983657
 
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