Anti NOD2 - Cosmo Bio Co.,Ltd.

Antibodies

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Anti NOD2 Antibody

Catalog No.: CAC-THU-A-NOD2
Size: 50UL
Price: ¥30000
$400
antigen/source: NOD2
host: Rabbit
Label: Unlabeled
Purity: Affinity Purified
Application: Western Blot
Immunohistochemistry
Flow Cytometry
Storage: -20C
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Immunogen: Porcine
Isotype: IgG

Other:

 Background 
A cytosolic surveillance system mediated by the nucleotide-binding oligomerization domain (NOD) proteins plays an important role in recognizing intracellular microbe-associated molecular patterns (MAMPs). NOD2 recognizes low-molecularpeptidoglycan fragments, such as muramyl dipeptide (MDP). Intracellur immunostaining of porcine
NOD2-expressing cells with this antibody shows that porcine NOD2 is located in the cytosol and also appeared enriched
close to the cell membrane. Thisantibody serve as powerful tools for biochemical and immunohistochemical analyzes of
porcine NOD2 and for understanding the mechanisms of NOD2-mediated immune system in pigs.
 Specificity 
Porcine NOD2
 Cross reactivity 
Reacts with porcine. Not yet tested in other species.
[Application notes Recommended dilutions ]
E Immunohistochemistry: 1/25-1/500
E Flow cytometry: 1/50-1/500
E Western blotting: 1/25-1/500
Other applications have not been tested.
Optimal dilutions/concentrations should be determined by the end user.


Reference:

•  Tohno M, Ueda W, Azuma Y, Shimazu T, Katoh S, Wang JM, Aso H, Takada H, Kawai Y, Saito T, Kitazawa H., Mol Immunol. 2008 Jan; 45(1):194-203. PMID: 17559936
 
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