Anti Importin α 3/KPNA4/Qip1 - Cosmo Bio Co.,Ltd.

Antibodies

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Anti Importin α 3/KPNA4/Qip1 Antibody

Catalog No.: BAM-70-325-EX
Size: 200UG
Price: ¥34500
$460
antigen/source: Importin α 3 / Qip1KPNA4
host: Rat
Purity: Purified
Application: Western Blot
catalog info: Catalog 2012-p56
Storage: -20C
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Isotype: IgG2aâ╚
Clone: 3D10
component: 1. Western blotting (250~500 fold dilution)
2. ELISA

Other:

 Background 
Importinâ┐ proteins play a pivotal role in the import of proteins from the cytoplasm to the nucleus. Importinâ┐proteins shuttle between nucleus and cytoplasm, bind nuclear localization signal (NLS)-bearing proteins, and mediate the protein import into the nucleus with importin â└.Several importinâ┐ isotypes have been identified, each exhibiting differential recognition and nuclear transport, probably via preferential binding to a particular NLS. The importinâ┐3 (KPNA4, Qip1) is amember of the importinâ┐ family of proteins belonging to the Qip1 subfamily. The antibody was purified from the serum-free cultured medium of the hybridoma under mild conditions by proprietary chromatography processes.



 IMAGE1



Fig.1 Detection of importin α3 (58 kD) by Western blotting using the antibody 3D10. Sample is the total cell extract. lane1: HeLa (human) lane2: COS7 (simian) lane3: L929 (mouse) lane4: NRK (rat) lane5: BHK (hamster) lane6: MDBK (bovine)

Reference:

•  Yoneda Y. Genes Cells 5: 777-787 (2000) PMID: 11029654
•  Miyamoto Y. et al., J Bio Chem 272:26375-26381 (1997) PMID: 9334211
•  Sakaguchi N. et al., Hybrid Hybridomics 22: 397-400 (2003) PMID: 14683601
•  Yasuhara N. et al., Nat Cell Biol 9:72-79 (2007) PMID: 17159997
 
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