Anti Sugar chain [Fuc α 1-2Gal β 1-3GlcNAc β 1-] - Cosmo Bio Co.,Ltd.

Antibodies

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Anti Sugar chain [Fuc α 1-2Gal β 1-3GlcNAc β 1-] Antibody

Catalog No.: KAN-02102-96-EX
Size: 50UL
[100 g / mL]
Price: ¥21000
$280
antigen/source: Gastric mucin
host: Mouse
Label: Unlabeled
Application: IHC paraffin embedding section
Enzyme Linked Immunosorbent Assay
Storage: -20C
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Immunogen: Rat
Isotype: IgM
Clone: RGM21
Shape: Liquid

Other:

 Background 
RGM21 is a mouse monoclonal antibody raised against the mucins purified from normal rat gastric mucosa, and
recognizes mucin-type carbohydrate antigens containing a blood group H (type 1 chain) sequence. The RGM21 antigens
are mainly expressed on normal gastric surface mucous cells in the gastrointestinal tract of mammalian. This antibody is
a useful tool for elucidating the biological role of the specific sugar chain.
 Specificity 
Glycoproteins that contain sugar chains including a blood group H (type 1 chain) sequence
Epitope : Sugar chain motif; Fuc1-2Gal1-3GlcNAc1-R
 Application 
E ELISA : 1/10 - 1/1000
E Immunohistochemistry: 1/100 - 1/1000 (formalin-fixation, paraffin-embedded)

Other applications have not been tested.
Optimal dilutions/concentrations should be determined by the end user.



 IMAGE1



Fig.1 Immunohistochemistry

Reference:

•  K. Ishihara.et al.,Glycoconj. J. 13(5), 857-864.(1996) PMID: 8910013
•  Y. Goso.et al.,J Biochem.126(2). 375-381.(1999) PMID: 10423532
•  H Hayashida.et al.,Biomed Res. 21(2). 95-103.(2000)
•  H Hayashida.et al.,Scand J Gastroenterol. 36(5). 467-473.(2001) PMID: 11346198
•  Y Goso.et al.,Seikagaku. 75(8). 901. (2003)
•  Y Goso.et al.,J Biochem. 133(4). 453-460. (2003) PMID: 12761292
•  T Ikezawa.et al.,J Gastroenterol. 39(2). 113-119. (2004) PMID: 15069617
•  Y Saegusa.et al.,Scand J Gastroenterol. 43(1). 59-65.(2008) PMID: 18938749
•  Y Saegusa.et al.,Scand J Gastroenterol. 43(5). 531-537.(2008) PMID: 18415744
 
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