Anti Sugar chain [GalNAc α 1-3Gal β 1-] - Cosmo Bio Co.,Ltd.

Antibodies

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Anti Sugar chain [GalNAc α 1-3Gal β 1-] Antibody

Catalog No.: KAN-02103-96-EX
Size: 50UL
[100 g / mL]
Price: ¥21000
$280
antigen/source: Gastric mucin
host: Mouse
Label: Unlabeled
Application: IHC paraffin embedding section
Enzyme Linked Immunosorbent Assay
Storage: -20C
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Immunogen: Rat
Isotype: IgM
Clone: RGM22
Shape: Liquid

Other:

 Background 
RGM22 is a mouse monoclonal antibody raised against
the mucins purified from normal rat gastric mucosa, and
recognizes mucin-type carbohydrate antigens containing a terminal GalNAc1-3Gal sequence. The RGM22 antigens are
mainly expressed on normal g gastric mucosal cells (pyloric gland cells) in the gastrointestinal tract of mammalian. This
antibody is a useful tool for elucidating the biological role of the specific sugar chain.
 Specificity 
Glycoproteins thatcontain sugar chains including a GalNAc1-3Gal sequence
Epitope : Sugar chain motif; GalNAc1-3Gal1-R
 Application 
E ELISA : 1/10 - 1/1000
E Immunohistochemistry: 1/100 - 1/1000 (formalin-fixation, paraffin-embedded)

Other applications have not been tested.
Optimal dilutions/concentrations should be determined by the end user



 IMAGE1



Fig.1 Immunohistochemistry

Reference:

•  K. Ishihara.et al.,Glycoconj. J. 13(5), 857-864.(1996) PMID: 8910013
•  T Chimuro.et al.,Seikagaku.77(8). 881.(2005)
•  T Chimuro.et al.,Seikagaku.A12744(1P-A-019).(2006)
 
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