Anti Sugar chain [GalNAc α 1-3(Fuc α 1-2)Gal β 1-] - Cosmo Bio Co.,Ltd.

Antibodies

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Anti Sugar chain [GalNAc α 1-3(Fuc α 1-2)Gal β 1-] Antibody

Catalog No.: KAN-02104-96-EX
Size: 50UL
[100 g / mL]
Price: ¥21000
$280
antigen/source: Gastric mucin
host: Mouse
Application: IHC paraffin embedding section
Enzyme Linked Immunosorbent Assay
Storage: -20C
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Immunogen: Rat
Isotype: IgM
Clone: RGM26
Shape: Liquid

Other:

 Background 
RGM26 is a mouse monoclonal antibody raised against the mucins purified from normal rat gastric mucosa, and recognizes mucin-type carbohydrate antigens containing a blood group A antigen. The RGM26 antigens are mainly
expressed onnormal gastric mucosal cells (pyloric gland cells) in the gastrointestinal tract of mammalian. In addition,
related antigens have been reported to found in the colon and the surface of erythrocytes. This antibody is a useful tool
for elucidatingthebiological role of the specific sugar chain.
 Specificity 
Glycoproteins that contain sugar chains including a blood group A sequence
Epitope : Sugar chain motif; GalNAc1-3(Fuc1-2)Gal1-R
 Application 
E ELISA : 1/10-1/1000
E Immunohistochemistry: 1/100 - 1/1000 (formalin-fixation, paraffin-embedded)
Other applications have not been tested.
Optimal dilutions/concentrations should be determined by the end user.



 IMAGE1



Fig.1 Immunohistochemistry

Reference:

•  K. Ishihara.et al.,Glycoconj. J. 13(5), 857-864.(1996) PMID: 8910013
•  H Hayashida.et al.,Biomed Res. 21(2). 95-103.(2000)
•  T Ichikawa.et al.,Dig Dis Sci. 45(3). 606-613.(2000) PMID: 10749340
•  TIkezawa.et al., J Gastroenterol. 39(2). 113-119.(2004) PMID: 15069617
•  T Chimuro.et al.,Seikagaku.A12744(1P-A-019).(2006)
•  Y Saegusaet al.,Scand J Gastroenterol. 43(5). 531-537.(2008) PMID: 18415744
•  Y Ito.et al.,J Agric Food Chem. 56(24). 12122-12126.(2008) PMID: 19035783
 
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