Anti Sugar chain [GalNAc α 1-3(Fuc α 1-2)Gal β 1-3(Fuc α 1-4)GlucNAc β 1-] - Cosmo Bio Co.,Ltd.

Antibodies

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Anti Sugar chain [GalNAc α 1-3(Fuc α 1-2)Gal β 1-3(Fuc α 1-4)GlucNAc β 1-] Antibody

Catalog No.: KAN-02109-96-EX
Size: 50UL
[100 g / mL]
Price: ¥21000
$280
antigen/source: Gastric mucin
host: Mouse
Label: Unlabeled
Purity: Ig fraction - Protein G
Application: IHC paraffin embedding section
Enzyme Linked Immunosorbent Assay
Storage: -20C
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Immunogen: Human
Isotype: IgG1
Clone: HGM75
Reacts with: -
Shape: Liquid

Other:

 Background 
HGM75 is a mouse monoclonal antibody raised against the mucins purified from normal human gastric mucosa, and
recognizes mucin-type carbohydrate antigens containing a GalNAc1-3(Fuc1-2)Gal1-3(Fuc1-4)GlcNAc sequence.
The HGM75 antigens are mainly expressed on normal gastric surface mucous cells in the gastrointestinal tract of human.
In addition, related antigens have been reported to found in goblet cells of human colon. This antibody is a useful tool for
elucidating the biological role of the specific sugar chain.
[Immunogen]
Human Gastric mucin
 Specificity 
Glycoproteins that contain sugar chains including sequenceof blood group A and Lewis B
Epitope : Sugar chain motif; GalNAc1-3(Fuc1-2)Gal1-3(Fuc1-4)GlcNAc-R
 Application 
E ELISA : 1/10 - 1/1000
E Immunohistochemistry: 1/100 - 1/1000 (formalin-fixation, paraffin-embedded)

Other applications have not been tested.
Optimal dilutions/concentrations should be determined by the end user.



 IMAGE1



Fig.1 Immunohistochemistry

Reference:

•  E Dabelsteen.et al., Cancer Res. 48(1). 181-187.(1988) PMID: 2446741
2) YZ Wang.et al.,Histopathology. 37(3). 250-259.(2000) PMID: 10971701
 
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