Anti Sugar chain [GlcNAc α 1-4Gal β 1-4GlcNAc β 1-] - Cosmo Bio Co.,Ltd.

Antibodies

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Anti Sugar chain [GlcNAc α 1-4Gal β 1-4GlcNAc β 1-] Antibody

Catalog No.: KAN-02110-96-EX
Size: 50UL
[100 g / mL]
Price: ¥21000
$280
antigen/source: Gastric mucin
host: Mouse
Label: Unlabeled
Application: IHC paraffin embedding section
Enzyme Linked Immunosorbent Assay
Storage: -20C
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Immunogen: Human
Isotype: IgM
Clone: HGM504
Reacts with: -
Shape: Liquid

Other:

 Background 
HGM504 is a mouse monoclonal antibody raised against the mucins purified from normal human gastric mucosa, and
recognizes mucin-type carbohydrate antigens containing a GlcNAc1-4Gal1-4GlcNAc sequence. The HGM504
antigens are mainly expressed on normal gastric mucosal cells (mucosal neck cells and pyloric gland cells) and Brunner's
gland cells in the gastrointestinal tract of mammalian. This antibody is a useful tool for elucidating the biological role of the
specific sugar chain.
[Immunogen]
Human Gastric mucin
 Specificity 
Glycoproteins that contain sugar chains including a peripheral -linked GlcNAc residue
Epitope : Sugar chain motif; GlcNAc1-4Gal1-4GlcNAc1-R
 Application 
EELISA : 1/10 - 1/1000
E Immunohistochemistry: 1/100 - 1/1000 (formalin-fixation, paraffin-embedded)

Other applications have not been tested.
Optimal dilutions/concentrations should be determined by the end user.



 IMAGE1



Fig.1 Immunohistochemistry

Reference:

•  H Kuroyama.et al.,The Japanese Society of Carbohydrate Research ; JSCR. 28, 44. (2008)
 
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