Anti Sugar chain [Fuc α 1-2Gal β 1-4(Fuc α 1-3)GlcNAc β 1-] - Cosmo Bio Co.,Ltd.

Antibodies

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Anti Sugar chain [Fuc α 1-2Gal β 1-4(Fuc α 1-3)GlcNAc β 1-] Antibody

Catalog No.: KAN-02111-96-EX
Size: 50UL
[100 g / mL]
Price: ¥21000
$280
antigen/source: Gastric mucin
host: Mouse
Label: Unlabeled
Application: IHC paraffin embedding section
Enzyme Linked Immunosorbent Assay
Storage: -20C
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Immunogen: Human
Isotype: IgG1
Clone: HGM505
Reacts with: -
Shape: Liquid

Other:

 Background 
HGM505 is a mouse monoclonal antibody raised against the mucins purified from normal human gastric mucosa, and
recognizes mucin-type carbohydrate antigens containing a blood group Lewis Y sequence. The HGM505 antigens are
mainly expressed on normal gastric surface mucous cells in the gastrointestinal tract of mammalian. In addition, related
antigens have been reported to found in the colon and the surface of erythrocytes. This antibody is a useful tool for
elucidating thebiological role of the specific sugar chain.
[Immunogen]
Human Gastric mucin
 Specificity 
Glycoproteins that contain sugar chains including a blood group Lewis Y sequence
Epitope : Sugar chain motif; Fuc1-2Gal1-4(Fuc1-3)GlcNAc1-R
 Application 
E ELISA : 1/10 - 1/1000

E Immunohistochemistry: 1/100 - 1/1000 (formalin-fixation, paraffin-embedded)

Other applications have not been tested.

Optimal dilutions/concentrations should be determinedby the end user



 IMAGE1



Fig.1 Immunohistochemistry

Reference:

•  R Kannagi. et al., J Biol Chem. 260(10), 6410-6415.(1985) PMID: 3997830
•  J Sakamoto.et al.,Cancer Res. 46(3), 1553-1561. (1986) PMID: 3510728
•  HP Wirth.et al.,Infect Immun. 64(11), 4598-4605.(1996) PMID: 8890213
•  M Dettke.et al.,J Leukoc Biol., 68(4), 511-514 (2000) PMID: 11037972
 
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