Anti Mucin M-GGMC-1 [GlcNAc α 1-] - Cosmo Bio Co.,Ltd.

Antibodies

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Anti Mucin M-GGMC-1 [GlcNAc α 1-] Antibody

Catalog No.: KAN-25503-96-EX
Size: 1ML
Price: ¥105000
$1400
antigen/source: Gastric mucin
host: Mouse
Label: Unlabeled
Application: IHC paraffin embedding section
Enzyme Linked Immunosorbent Assay
Storage: 4C
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Immunogen: Rat
Isotype: IgM
Clone: HIK1083
Reacts with: -
Shape: Lyophilized

Other:

 Background 
M-GGMC-1 is a mouse monoclonal antibody which recognizes the peripheral alpha-linked N-acetylglucosamine residue
present in the carbohydrate moiety of the mucin molecule and reacts with oligosaccharides bearing a peripheral
-GlcNAc structure. M-GGMC-1 recognizes the mucins derived from the normal gastric mucosal cells (mucosal neck
cells and pyloric gland cells) and Brunner's gland cells in the gastrointestinal tract of mammalian. In addition, M-GGMC-1
can be used to detect adenoma malignum in the uterine cervical glands have been reported. This antibody is a useful tool
for elucidating the biological role of the specific sugar chain.
[Immunogen]
Rat Gastric mucin
 Specificity 
Mucin-type oligosaccharides bearing a peripheral -linked GlcNAc strucure
Epitope : Sugar chain motif; GlcNAc1-R
 Application 
E ELISA : 1/10 - 1/1000
E Immunohistochemistry: 1/5 - 1/50 (formalin-fixation, paraffin-embedded)

Other applications have not been tested.
Optimal dilutions/concentrations should be determined by the end user.



 IMAGE1



Fig.1 Immunohistochemistry

Reference:

•  K. Ishihara. et al., Biochem. J. 318(Pt2), 409-416. (1996) PMID: 8809027
•  N Nakamura. et al., J Histochem Cytochem. 46(7). 793-801.(1998) PMID: 9632738
•  T. Honda. et al., Am J Clin Pathol. 109(4). 423-430. (1998) PMID: 9535396
•  K Ishii. et al., Virchows Arch. 432(4). 315-322.(1998) PMID: 9565340
•  J Nakayama. et al., Proc Natl Acad Sci USA. 96(16). 8991-8996.(1999) PMID: 10430883
•  T Ikezawa. et al., J Gastroenterol. 39(2). 113-119.(2004) PMID: 5069617
•  S Kubota. et al., Clin Chim Acta. 377(1-2). 261-267.(2007) PMID: 17134689
•  M Iijima. et al., Am J Dermatopathol. 29(5). 452-456. (2007) PMID: 17890913
 
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