Osteoclast Culture Kit V-1 - Cosmo Bio Co.,Ltd.

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Osteoclast Culture Kit V-1

Catalog No.: PMC-OSC15-COS
Size: 1SET
Price: see also
#PMC-OSC15CCOS
Size 1
Storage: -20C & Liquid Nitrogen
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Immunogen: Human
Purpose: To evaluate osteoclast formation and activation.
component: Osteoclast Culture Kit (Human) (PMC-OSC15-COS) consists of frozen osteoclast precursors isolated from human bone marrow,differentiation medium including M-CSF and RANKL.
[Components of Media]
PMC-OSCMW-COS and PMC-OSCMH-COS are complete media formulated for optimal culture of human osteoclast in vitro. These are sterile, liquid basal media (ƒ¿-MEM) which contain essential and non-essential amino acids, vitamins, other organic compounds, trace minerals, inorganic salts, growth factors, hormones, fetal bovine serum, and antibiotics. In addition, PMC-OSCMH-COS, which is used to differentiate preosteoclast to mature osteoclast, contains 50 ng /mL M-CSF and 100 ng /mL RANKL.

Other:

 Background 
Bone metabolism is composed of balanced osteogenesis and bone resorption. Research studies have shown that bone marrow cells can be differentiated into osteoclasts using M-CSF (Macrophage Colony Stimulating Factor) and RANKL (Receptor Activator of NF kappa B Ligand).



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