Anti COMP Fragment (2127F5) - Cosmo Bio Co.,Ltd.



Anti COMP Fragment (2127F5) Antibody

Catalog No.: CAC-PRPG-CPF-M02
Size: 2ML
Price: ¥55000
antigen/source: COMP Fragment (2127F5)
host: Mouse
Purity: Supernatant
Application: Western Blot
IHC paraffin embedding section
Enzyme Linked Immunosorbent Assay
Storage: -20C
Immunogen: Human
Isotype: IgG1
Clone: 2127F5
Reacts with: Human


COMP - Cartilage oligomeric matrix protein - belongs to the thrombospondin family of ECM components and is a prominent multidomain glycoprotein of cartilage, accounting for up to 1% of the wet weight of articular tissues and having anapproximate Mr of 97 kDa [1-4]. COMP may also be found in tendon, bone (i.e. osteoblasts), ligament, certain smooth muscles and synovium and more recently has been discovered to be a primary constituents of the dermal ECM [5]. In the ECM COMP is present in a pentameric, disulfide-bonded complex of an Mr of about 550 kDa, often seen associated with the chondrocyte cell surface [3, 5]..
Recombinant EGF domain of human COMP
COMP (Cartilage Oligomeric Matrix Protein)


Left panel: Western blotting on recombinant COMP produced in HEK293 cells after SDS-PAGE under reducing conditions on 8% gels. Lanes 1 and 2 from left show secreted and cell-bound COMP, whereas the two adjacent lanes show the controls. Right panels: immunohistochemical stainings of human articular cartilage at lower (left) and higher magnification (right).


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