Anti HSD3B2 - Cosmo Bio Co.,Ltd.

Antibodies

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Anti HSD3B2 Antibody

HSD3B2, 3-Beta-HSD II, 3b]hydroxysteroid dehydrogenase/isomerase@type II, hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2

Catalog No.: KAL-KG619
Size: 50UG
[0.25mg/ml]
Price: ¥60000
$800
antigen/source: HSD3B2
host: Mouse
Description: [Immunogen]a.a.8-28, N-terminal
Label: Unlabeled
Application: Western Blot
Enzyme Linked Immunosorbent Assay
Immunohistochemistry
Storage: -20C
@
Immunogen: Human
Isotype: IgG1
Clone: 12E4
Reacts with: Human
Gene ID:3284

Other:

 Features 
HSD3B2 is a bifunctional enzyme, that catalyzes the oxidative conversion of Delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. The HSD3B2 enzymatic system plays a crucial role in the biosynthesis of allclasses of hormonal steroids.
[Subcellular location]
Endoplasmic reticulum membrane; Single-pass membrane protein. Mitochondrion membrane; Single-pass membrane protein.
[Tissue specificity]
Expressed in adrenal gland, testis and ovary.
[Involvement in disease]
Adrenal hyperplasia 2
[Sequence similarities]
Belongs to the 3-beta-HSD family.



 IMAGE1



Western Blotting Sample: COS7 cells transfected with HA-tagged HSD3B2/pEZ or others Lane 1; COS7 cells transfected with empty vector pEZ Lane 2; COS7 cells transfected with HA-tagged HSD3B1/pEZ Lane 3; COS7 cells transfected with HA-tagged HSD3B2/pEZ Provided from Dr. Doi M. Graduate School of Pharmaceutical Sciences, Kyoto University

Reference:

Doi M. et al., J. Clin. Endocrinol. Metab. 2014, 99, E257-E262.
 
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