Function : The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting.
Sequence similarities : Belongs to the calcium channel beta subunit family. Contains 1 SH3 domain.
Anti Mouse Cacnb4 Polyclonal Antibody
Background
Application
| ELISA | WB | IHC | ICC |
|---|---|---|---|
| 1.0 μg/mL | 1.0 μg/mL | Not tested | 1.0-5.0 μg/mL |
| IP | FCM | IF | Neutralization |
| 5.0 μg/mL | Not tested | Not tested | Not tested |
Character
| Type | Polyclonal Antibody |
| Immunogen | Partial peptide of Mouse Cacnb4 C-terminal region |
| Raised in | Rabbit |
| Source | Rabbit Serum |
| Purification notes | Antigen Affinity |
| Cross Reactivity | |
| Concentration | 0.25 mg/mL |
| Contents (Volume) | 25 μg (100 μL/vial) |
| Label | Unlabeled |
| Buffer | PBS [containing 2% Block Ace as a stabilizer, 0.1% Proclin as a bacteriostat] |
| Storage | Store below -20 °C. Once thawed, store at 4 °C. Repeated freeze-thaw cycles should be avoided. |
<Reference>
1. Kiyonaka S, et al. RIM1 confers sustained activity and neurotransmitter vesicle anchoring to presynaptic Ca2+ channels. Nat Neurosci. 2007 Jun;10(6):691-701. *Application Reference
