Function : Calcium channel which may play a role in metastasis suppression. May act as a spontaneously active, calcium-permeable plasma membrane channel.
Tissue specificity : Expressed in eye. Not detected in brain, lung, liver, heart, kidney, spleen or small intestine. Also expressed at high levels in poorly metastatic variants of B16 melanoma and at much reduced levels in highly metastatic variants of B16 melanoma.
Sequence similarities : Belongs to the transient receptor family. LTrpC subfamily.
Anti Mouse Trpm1 Polyclonal Antibody
Background
Application
| ELISA | WB | IHC | ICC |
|---|---|---|---|
| 1.0 μg/mL | 2.0 μg/mL | Not tested | Not tested |
| IP | FCM | IF | Neutralization |
| Not tested | Not tested | Not tested | Not tested |
Character
| Type | Polyclonal Antibody |
| Immunogen | Partial peptide of Mouse Trpm1 middle region |
| Raised in | Rabbit |
| Source | Rabbit Serum |
| Purification notes | Antigen Affinity |
| Cross Reactivity | |
| Concentration | 0.25 mg/mL |
| Contents (Volume) | 25 μg (100 μL/vial) |
| Label | Unlabeled |
| Buffer | PBS [containing 2% Block Ace as a stabilizer, 0.1% Proclin as a bacteriostat] |
| Storage | Store below -20 °C. Once thawed, store at 4 °C. Repeated freeze-thaw cycles should be avoided. |
<Reference>
1. Lis A, et al. Transcriptional regulation and processing increase the functional variability of TRPM channels. Naunyn Schmiedebergs Arch Pharmacol. 2005 Apr;371(4):315-24.
