Anti Human TACSTD1 Polyclonal Antibody

[WB] human colon tissue lysate

[WB] A-431 cell lysate

[WB] TACSTD1 transfected 293T

[IF] HeLa cell

<Summary>
# Function: May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection.
# Subcellular location: Membrane; Single-pass type I membrane protein.
# Tissue specificity: This protein is expressed in almost all epithelial cell membranes but not on mesodermal or neural cell membranes. Found on the surface of adenocarcinomas.
# Sequence similarities: Belongs to the EPCAM family. Contains 1 thyroglobulin type-1 domain.

<Reference>
1.Strnad J., et al.  "Molecular cloning and characterization of a human adenocarcinoma/epithelial cell surface antigen complementary DNA." Cancer Res. 49:314-317(1989)
2. Perez M.S., et al.  "Isolation and characterization of a cDNA encoding the KS1/4 epithelial carcinoma marker." J. Immunol. 142:3662-3667(1989)
3. Simon B., et al.  "Epithelial glycoprotein is a member of a family of epithelial cell surface antigens homologous to nidogen, a matrix adhesion protein." Proc. Natl. Acad. Sci. U.S.A. 87:2755-2759(1990)