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Anti Human NPFFR1 Monoclonal Antibody


Application

ELISA WB IHC ICC
1.0 Not tested 5.0-10 Not tested
IP FCM IF Neutralization
Not tested Not tested Not tested Not tested

 


[IHC] Rat testis tissue

 

<Summary>
#. Function: Receptor for NPAF (A-18-F-amide) and NPFF (F-8-F-amide) neuropeptides, also known as morphine-modulating peptides. Can also be activated by a variety of naturally occurring or synthetic FMRF-amide like ligands. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
# Sequence similarities: Belongs to the G-protein coupled receptor 1 family.

Feature and Advantages

Type Monoclonal Antibody
Immunogen Partial peptide of Human NPFFR1-3rd extracellular domain
Raised in GANP® mouse
Source Serum-free medium
Purification ProteinG
Cross Reactivity Rat
Concentration 0.25 mg/mL
ContentsiVolumej 50 μgi200 μL/vial)
Label Unlabeled
Buffer PBS [containing 2% Block Ace as a stabilizer, 0.1% Proclin as a bacteriostat]
Storage Store below –20Ž. Once thawed, store at 4Ž. Repeated freeze-thaw cycles should be avoided..

 

<Reference>
1. Gouardères C, et al. Detailed distribution of neuropeptide FF receptors (NPFF1 and NPFF2) in the rat, mouse, octodon, rabbit, guinea pig, and marmoset monkey brains: a comparative autoradiographic study. Synapse. 2004 Mar 15;51(4):249-69.
2. Goncharuk V, et al. Distribution of the neuropeptide FF1 receptor (hFF1) in the human hypothalamus and surrounding basal forebrain structures: immunohistochemical study. J Comp Neurol. 2004 Jul 5;474(4):487-503.

 

This product is generated from GANP® mice