| ELISA | WB | IHC | ICC |
|---|---|---|---|
| 1.0 | Not tested | 5.0 | Not tested |
| IP | FCM | IF | Neutralization |
| Not tested | Not tested | Not tested | Not tested |
[IHC] Rat thymus tissue
[IHC] Rat soleen tissue
<Summary>
#. Function: The H4 subclass of histamine receptors could mediate the histamine signals in peripheral tissues. Displays a significant level of constitutive activity (spontaneous activity in the absence of agonist).
# Tissue specificity: Expressed primarily in the bone marrow and eosinophils. Shows preferential distribution in cells of immunological relevance such as T-cells, dendritic cells, monocytes, mast cells, neutrophils. Also expressed in a wide variety of peripheral tissues, including the heart, kidney, liver, lung, pancreas, skeletal muscle, prostate, small intestine, spleen, testis, colon, fetal liver and lymph node..
# Sequence similarities: Belongs to the G-protein coupled receptor 1 family.
