Processing protease function study tool

Anti PACE4


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Background

PACE4 is one kind of a processing protease family controlling cytodifferentiation and a morphosis, and the structure and function are clarified by the study group of Tuji et al, the University of Tokushima.
It is said that PACE4 plays a particularly important role in outbreak such as the organogeny and differentiation process. Lately, it is suggested that it participate in activation of the matrix metalloprotease (MMP), and participate in metastasis and the dampness of cancer.

References

1.@Nagahama et al. (1998) Biosynthetic processing and quaternary interaction of proprotein convertase SPC4 (PACE4). FEBS Letters 434, 155-159
2.@Tsuji et al. (2003) Secretory proprotein convertases PACE4 and PC6A are heparinbinding proteins which are localized in the extracellular matrixBiochim. Biophys. Acta 1645, 95-104
3.@Taniguchi et al (2002) A critical role for the carboxy terminal region of the proprotein convertase, PACE4A, in the regulation of its autocatalytic activation coupled with secretion. Biochem. Biophys. Res. Commun. 290, 878-884

Product List

Product Name Cat# Quantity Price

Anti PACE4 (homoB domain), Human (Rabbit)  DataSheet

CAC-SK-T01-001

100 UL ¥40,000
$534

Anti PACE4 propeptide, Human (Rabbit)  DataSheet

CAC-SK-T01-002

100 UL ¥40,000
$534

Anti ASH-1, Human (Rabbit)  DataSheet

CAC-SK-T01-003

100 UL ¥40,000
$534

Anti ASH-2, Human (Rabbit)  DataSheet

CAC-SK-T01-004

100 UL ¥40,000
$534

Anti Metastin, Human (Rabbit)  DataSheet

CAC-SK-T01-005

100 UL ¥40,000
$534

To be used for research only. DO NOT use for human gene therapy or clinical diagnosis.


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