Anti PMIS2


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Background

PMIS2 might function both as the ultimate factor regulating sperm transport into the oviducts and in modulating sperm–zona binding.

Application

 

Fig.1. Analysis of PMIS2 protein expression in testes extracts from wild-type (+/+) and Pmis2 knockout (-/-) mice by western blotting with anti-PMIS2 antibody. Testes and sperm were lyzed in lysis buffer containing 1% Triton-X100 and extracts were prepared as supernatants of lysates after centrifugation. Samples were reacted with anti-PMIS2 antibody at 1/1,000 dilution. The difference in predicted molecular mass (11 kDa) and the band position (18 kDa) of PMIS protein might be due to glycosylation.

References

# Yamaguchi R., et al. Mice expressing aberrant sperm-specific protein PMIS2 produce
normal-looking but fertilization-incompetent spermatozoa. Mol Biol Cell. 2012
Jul;23(14):2671-9. PMID: 22621904

Product List

Product Name Cat# Quantity Price

Anti PMIS2, Mouse (Rabbit)  DataSheet

BAM-73-055-EX

100 UL ¥34,500
$460

To be used for research only. DO NOT use for human gene therapy or clinical diagnosis.


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