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Human Keratinocyte Growth Factor ( KGF/ FGF7 )


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Background

Keratinocyte Growth Factor (KGF), also known as Fibroblast Growth Factor 7 (FGF-7), is a member of fibroblast growth factor (FGF) family. Although FGF-7 has heparin binding activity similar to FGF-1, its mitogenic activity is predominantly exhibited in keratinocytes. It is not effective to fibroblasts and endothelial cells.
The human FGF-7 lacking the signal sequence (1-31 aa) was expressed in E. coli and purified by the chromatographic procedures. This product is an intact enzyme without tag with 19 kDa size (Fig.) 

Data Link  GeneID: 2252, Gene Sequence: M60828.1,  Amino Acid Sequence: P21781

Application

1. Mitogen for epithelial cells
2. Western blot control for anti-FGF-7 antibodies
3. Acceleration of wound healing is implied.
4. Acceleration of hair development is implied. 

Specification


SDS-PAGE of human FGF-7

Activity  : The ED50 as determined by a cell proliferation assay using MTS assay kit (CellTiter 96, Promega) with human keratinocyte JCRB141cells was < 10 ng/ml.

Purity   :  >95% as determined by SDS-PAGE (CBB staining)

Form    :  1.0 mg / ml in PBS (10mM Na-phosphate, 150mM NaCl) pH7.2, 50% glycerol, filter-sterilized

<References>
1. Rubin JS et al.(1989) “Purification and characterization of a newly identified growth factor specific for epithelial cells.” Proc Natl Acad Sci USA 86: 802-806 PMID: 2915979
2. Aaronson SA et al. (1991) ”Keratinocyte growth factor. A fibroblast growth factor family member with unusual target cell specificity.” Ann NY Acad Sci 638:62-77 PMID: 1664700 

Product List

Product Name Cat# Quantity Price

Keratinocyte Growth Factor (KGF/FGF7), Human DataSheet

BAM-03-005-EX

50 UG ¥31,000
$414

Keratinocyte Growth Factor (KGF/FGF7), Human DataSheet

BAM-03-005-5EX

5*50 UG ¥94,500
$1260

Product Name Cat# Quantity Price

Epidermal Growth Factor, Human DataSheet

BAM-03-001-EX

50 UG ¥12,500
$167

Epidermal Growth Factor, Human DataSheet

BAM-03-001-5EX

5*50 UG ¥37,500
$500

Fibroblast Growth Factor 1, Human DataSheet

BAM-03-003-EX

50 UG ¥26,000
$347

Fibroblast Growth Factor 1, Human DataSheet

BAM-03-003-5EX

5*50 UG ¥78,000
$1040

Keratinocyte Growth Factor (KGF/FGF7), Human DataSheet

BAM-03-005-EX

50 UG ¥31,000
$414

Keratinocyte Growth Factor (KGF/FGF7), Human DataSheet

BAM-03-005-5EX

5*50 UG ¥94,500
$1260

“Human Keratinocyte Growth Factor ( KGF/ FGF7 )” also belongs to the following categories.