• HOME
  • Products
  • Hepatitis B Virus Surface Antigen (HBsAg), L-protein, Recombinant

useful for the immunological study in HBV and the research of the infection mechanism

Hepatitis B Virus Surface Antigen (HBsAg), L-protein, Recombinant


print

Background

HBsAg is the surface antigen of Hepatiis B virus (HBV). HB‚“Ag is known to be present in blood if HBV infected patients, and used as a important diagnostic maker of HBV infection. HBsAg forms a small lipid particleidiameter 50 to 60nmjin which many antigen protein are present. Each antigen protein has three domains, called S, Pre-S1 and Pre-S2. L-type antigen contains all the three domains, M-type antigen contains S- and Pre-S2, and S-type antigen consisted of only S-domains. During the process of HBV infection, Pre-S1 domain plays a key role for host (haptic) cell recognition, and Pre-S2 domain is essential for cell penetration. In infected patients, hepatic cells produces a lot of non-infectious S-type HBsAg (HBV mimetics without genome). The detection of serum Pre-S2 and Pre-S1 antigen is, therefore, very important to reveal the mechanism of HBV infection. Beacle has a decade of R&D history on HBsAg and related materials, and developed the production process of various HBsAgs and Bionanocapsule (a kind of form of HBsAg) for DDS purpose. We now supply these HBsAg-related products.

Feature and Advantages

Our HBs antigens are all recombinant antigen produced in yeast or E.coli. Therefore, antigens shows stable quality, and does not cause HBV infections. We also supply HBs-related antibodies, good for western and ELISA.

Activity

Pre-S1 activity is more than 1000 units
(Unit are arbitrary scale determined in Beacle using Pre-S1 detecting ELISA system)

Structure

Nano size particles having antigen protein floating in lipid bilayer. The mean particle size is 60 to 70nm as determined dynamic light scattering methods (20 nm as determined by electron microscopy)

SDS-PAGE with silver staining

Product List

Product Name Cat# Quantity Price

Hepatitis B Virus Surface Antigen (HBsAg), L-protein DataSheet ,

BEC-BCLAG01

100 UG ¥80,000
$1067

HBsAg with high antigenic activity (HBsAg-XT) DataSheet ,

BEC-BCL-AGX-01

30 UG N/A

HBsAg with high antigenic activity (HBsAg-XT) DataSheet ,

BEC-BCL-AGX-02

100 UG ¥80,000
$1067

Anti HBs Pre-S1 (Rabbit)  DataSheet

BEC-BCL-ABP1-01

100 UG ¥30,000
$400

Anti HBs, S-protein (Rabbit)  DataSheet

BEC-BCL-ABPS-01

100 UG ¥30,000
$400

HBsAg, Pre-S1 peptide DataSheet ,

BEC-BCL-AGS1-01

100 UG see also
# BEC-BCLAGS102
Size 100

HBsAg, Pre-S1 peptide Thioredoxin-His Tag DataSheet ,

BEC-BCL-AGS1-21

100 UG ¥60,000
$800

HBsAg, Pre-S2 peptide DataSheet ,

BEC-BCL-AGS2-01

100 UG ¥80,000
$1067

HBsAg, Pre-S2 peptide Thioredoxin-His Tag DataSheet ,

BEC-BCL-AGS2-21

100 UG ¥60,000
$800

To be used for research only. DO NOT use for human gene therapy or clinical diagnosis.



“Hepatitis B Virus Surface Antigen (HBsAg), L-protein, Recombinant” also belongs to the following categories.