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Anti NƒĂ-(carboxymethyl) lysine (CML) monoclonal antibody



Nε-(carboxymethyl) lysine (CML) is reported as a major antigenic AGE structure. Recent studies demonstrate that CML is generated by the oxidative cleavage of Amadori products by hydroxyl radical, peroxynitrite and hypochlorous acid, thus suggesting CML to be an important biological marker of oxidative stress in vivo.


<CML production pathway>
CML production pathway


Western blotting, 1/200 to 1/400
Immunohistochemistry, 1/100 to 1/200
ELISA, 1/200 to 1/400


CML Application


1.Mera K., Nagai M., Brock JW., Fujiwara Y., Imai H., Murata T., Maruyama T., Baynes JW., Otagiri M., Nagai R. Glutaraldehyde is an Effective Cross-linker for Production of Antibodies Against Advanced Glycation End Products. J. Immunol. Methods 334 (1-2), 82-90 (2008)

Product List

Product Name Cat# Quantity Price

Anti N(ε)-(carboxymethyl) lysine (CML) (Mouse)  DataSheet


100 UL ¥50,000

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