Anti GA-pyridine monoclonal antibody


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Background

Glycolaldehyde formed as a result of the myeloperoxidase-H2O2 (MPO) reaction can react with proteins to yield various AGEs. Recently, a novel specific GA-derived AGE, called GA-pyridine, has been described in foam cells and the extracellular matrix of human atherosclerotic fibrotic lesions, glomerular mesangial and Bruch’s membrane and choroid.

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Application

Western blotting, 1/200 to 1/2000
Immunohistochemistry, 1/200 to 1/400
ELISA, 1/200 to 1/400

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References
1) Nagai R., Hayashi CM., Xia L., Takeya M., Horiuchi S: Identification in human atherosclerotic @@lesions of GA-pyridine, a novel structure derived from glycolaldehyde-modified proteins. J Biol Chem. 277, 48905-48912 (2002)
2) Glenn JV., Mahaffy H., Wu K., Smith G., Nagai R., Simpson DAC., Boulton ME., Stitt AW. AGE-modified substrate induces global gene expression changes in ARPE-19 monolayers: relevance to lysosomal dysfunction and lipofuscin accumulation. Invest. Ophth. Vis. Sci. 50, 441-451 (2009)

Product List

Product Name Cat# Quantity Price

Anti GA-pyridine (Mouse) Unlabeled DataSheet

CAC-AGE-M03

100 UL ¥50,000
$667

“Anti GA-pyridine monoclonal antibody” also belongs to the following categories.