Anti uroplakin Ia polyclonal antibody


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Background

Uroplakin is a protein that is specific for the urothelium and it is composed of subtypes Ia, Ib, II, and III. The protein exists on cell surfaces. While the protein has been studied in the field of basic research on the urothelium, it has been suggested that the protein is useful as a tumor marker in clinical medicine.

Application

Western blotting, 1/10,000
Immunohistochemistry, 1/200

[Western blot analysis]
Recombinant human UP Ia protein combined with thioredoxin (Mr 35kDa)


Lane1 : SDS-PAGE
Lane2 : negative control
Lane3 : anti-human UP1a antibody
Lane4 : anti-human UP1a antibody absorbed by recombinant human UP1aprotein 0.1μg
Lane5 : anti-human UP1a antibody absorbed by recombinant human UP1aprotein 10μg
Lane6 : anti-human UP1a antibody absorbed by synthetic immunogen polypeptide 10μg

[Immunohistochemistry]
Urothelial cancer


AF superficial pattern (×40)

B: cytoplasmic p. (×40)

C: intercellular p. (×20)

D: micro luminal p. (×20)

<References>
1) Wu XR, et al: Uroplakins in urothelial biology, function, and disease. Kidney Int 75:1153-65, 2009
2) T Yuasa, et al : Expression of transitional cell-specific genes, uroplakina?a and?, in bladder cancer : Detection of circulating cancer cells in the peripheral blood of metastatic patients. Int J Urol 6 :286-292, 1999.

Product List

Product Name Cat# Quantity Price

Anti Uroplakin Ia, Human (Rabbit) Unlabeled DataSheet

CAC-TSS-P01

100 UL ¥45,000
$600

Product Name Cat# Quantity Price

Anti GGCT, Human (Mouse)  DataSheet

CAC-TSS-M01

100 UG ¥45,000
$600

Anti Calreticulin, Human (Mouse)  DataSheet

CAC-TSS-M02

100 UG ¥45,000
$600

Anti Calreticulin, Human (Mouse)  DataSheet

CAC-TSS-M03

100 UG ¥45,000
$600

To be used for research only. DO NOT use for human gene therapy or clinical diagnosis.



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