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Anti Cytokeratin18 (CK18) monoclonal antibody


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Background

Recently, it could be shown that the induction of CK 8/18 expression in non-malignant buccal mucosa cells resulted in a significant change of phenotypic characteristics after CK 8/18 transfection. These changes include an increased cellular motility, which might give first hints for an increased tumor aggressiveness and poor patient prognosis.

Application

Western blotting, 1/1,000 to 1/5,000
Immunocytochemistry, 1/100 to 1/500
Immunohistochemistry, 1/100 to 1/500

CAC_CE044A_1

Fig.1 Immunocytochemistry/ Immunofluorescence -
Cytokeratin-18(CK18) antibody (D2C7)
HeLa cells

CAC_CE044A_2

Fig.2 Western blot - Cytokeratin-18(CK18) antibody (D2C7)
1.HeLa, 2.COS1, 3.rat liver, 4.mouse liver total extracts

Optimal dilutions/concentrations should be determined by the end user.

References

1. Linder et al.,(2004) Determining tumor apoptosis and necrosis in patient serum using
cytokeratin 18 as a biomarker. Cancer Lett.,214,1-9.

Product List

Product Name Cat# Quantity Price

Anti Cytokeratin18 (CK18), Human (Mouse)  DataSheet

CAC-CE-044A

100 UL ¥58,000
$774

To be used for research only. DO NOT use for human gene therapy or clinical diagnosis.



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