Anti Human CACNB1 Polyclonal Antibody


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HGNC [ 1401 ]

Application

ELISA WB IHC ICC
Not tested 1.0 Not tested Not tested
IP FCM IF Neutralization
Not tested Not tested Not tested Not tested

(μg/mL)


[WB] CACNB1 transfected 293T cell lysate

 

< UniPlot Summary>
#@Function : The beta subunit of voltage-dependentcalcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting.
#  Subcellular location : Cell membrane › sarcolemma; Peripheral membrane protein; Cytoplasmic side.
#  Tissue specificity : Expressed in brain, heart and spleen (isoform 1 and 3) and in skeletal muscle (isoform 2).
#  Sequence similarities Belongs to the calcium channel beta subunit family.Contains 1 SH3 domain.

Character

Type Polyclonal Antibody
Immunogen Recombinant protein of full length Human CACNB1
Raised in mouse
Source Mouse Serum
Purification Protein A purified
Cross Reactivity  
Concentration 0.5 mg/mL
ContentsiVolumej 50μg /100μL)
Label Unlabeled
Buffer PBS, pH 7.2
Storage Store at - 20Ž long term, store at 4Ž short term. Avoid repeated freeze-thaw cycles.

<Reference>
1. Powers P.A., et al. "Skeletal muscle and brain isoforms of a beta-subunit of human voltage-dependentcalcium channels are encoded by a single gene." J. Biol. Chem. 267:22967-22972(1992)
2. Collin T., et al. "Molecular cloning of three isoforms of the L-type voltage-dependentcalcium channel beta subunit from normal human heart." Circ. Res. 72:1337-1344(1993)
3. Fukuda K., et al. "Cyclic AMP-dependent modulation of N- and Q-type Ca2+ channels expressed in Xenopus oocytes." Neurosci. Lett. 217:13-16(1996)

Product List

Product Name Cat# Quantity Price

Anti CACNB1, Human (Mouse) Unlabeled DataSheet

KAL-KB512

50 UG N/A

To be used for research only. DO NOT use for human gene therapy or clinical diagnosis.



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