Anti Human CLIC2 Polyclonal Antibody


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HGNC [ 2063 ]

Application

ELISA WB IHC ICC
Not tested 1.0 Not tested Not tested
IP FCM IF Neutralization
Not tested Not tested Not tested Not tested

(μg/mL)


[WB] human spleen tissue

[WB] CLIC2 transfected 293T cell lysate

 

< UniPlot Summary>
#@Function // Can insert into membranes and form chloride ion channels. Channel activity depends on the pH. Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions. Modulates the activity of RYR2 and inhibits calcium influx.
#@Subcellular location // Cytoplasm. Membrane; Single-pass membrane protein Probable. Note: Exists both as soluble cytoplasmic protein and as membrane protein with probably a single transmembrane domain.
#  Tissue specificity // Detected in adult brain, heart, liver, lung, spleen, stomach and testis. Expressed in fetal liver and adult skeletal muscle.
#  Sequence similarities // Belongs to the chloride channel CLIC family. Contains 1 GST C-terminal domain.

Character

Type Polyclonal Antibody
Immunogen Recombinant protein of full length Human CLIC2
Raised in mouse
Source Mouse Serum
Purification Protein A purified
Cross Reactivity Human
Concentration 1 mg/mL
ContentsiVolumej 50μg /50μL)
Label Unlabeled
Buffer PBS, pH 7.2
Storage Store at - 20Ž long term, store at 4Ž short term. Avoid repeated freeze-thaw cycles.

<Reference>
1. Heiss N.S., et al. "Genomic structure of a novel chloride channel gene, CLIC2, in Xq28." Genomics 45:224-228(1997)
2. Ross M.T., et al. "The DNA sequence of the human X chromosome." Nature 434:325-337(2005)
3. The MGC Project Team. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." Genome Res. 14:2121-2127(2004)

Product List

Product Name Cat# Quantity Price

Anti CLIC2, Human (Mouse) Unlabeled DataSheet

KAL-KB515

50 UG N/A

To be used for research only. DO NOT use for human gene therapy or clinical diagnosis.



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