Anti Human LAMP2 Polyclonal Antibody


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Application

ELISA WB IHC ICC
- 1 3 -
IP FCM IF Neutralization
- 1 3 -

(μg/mL)


[WB] human liver tissue lysate

[IHC] Paraffin embedded human salivary gland tissue

[IF] HeLa cell

[FCM] LAMP2 expressing 293 cells

 

< UniPlot Summary>
#@Function // Implicated in tumor cell metastasis. May function in protection of the lysosomal membrane from autodigestion, maintenance of the acidic environment of the lysosome, adhesion when expressedon the cell surface (plasma membrane), and inter- and intracellular signal transduction
#  Subcellular location // Cell membrane, Endosome membrane, Lysosome membrane; Single-pass type I membrane protein.
#  Tissue specificity // Isoform LAMP-2A is highly expressed in placenta, lung and liver, less in kidney and pancreas, low in brain and skeletal muscle. Isoform LAMP-2B is highly expressed in skeletal muscle, less in brain, placenta, lung, kidney and pancreas, very low in liver.
#  Sequence similarities // Belongs to the LAMP family.

Character

Type Polyclonal Antibody
Immunogen Recombinant protein of full length Human LAMP2
Raised in mouse
Source Mouse Serum
Purification Protein A purified
Cross Reactivity Human
Concentration 0.49 mg/mL
ContentsiVolumej 50μg / 102μL
Label Unlabeled
Buffer PBS, pH 7.2
Storage Store at - 20Ž long term, store at 4Ž short term. Avoid repeated freeze-thaw cycles.

<Reference>
1. Fukuda M., et al. "Cloning of cDNAs encoding human lysosomal membrane glycoproteins, h-lamp-1 and h-lamp-2. Comparison of their deduced amino acid sequences." J. Biol. Chem. 263:18920-18928(1988)
2. Konecki D.S., et al. "Complete cDNA sequence of human lysosome-associatedmembrane protein-2." Biochem. Biophys. Res. Commun. 205:1-5(1994)
3. Konecki D.S., et al. "An alternatively spliced form of the human lysosome-associatedmembrane protein-2 gene is expressed in a tissuespecific manner." Biochem. Biophys. Res. Commun. 215:757-767(1995)

Product List

Product Name Cat# Quantity Price

Anti LAMP2, Human (Mouse) Unlabeled DataSheet

KAL-KB477

50 UG N/A
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