Anti Human TIAM2 Polyclonal Antibody


print

Application

ELISA WB IHC ICC
- 1.0 - -
IP FCM IF Neutralization
- 1.0 - -

(μg/mL)

<Western blotting>

[WB] rat brain tissue lysate


[WB] TIAM2 transfected 293T cell lysate


[FCM] TIAM2 expressing 293 cells

 

<UniPlot Summary>
# Function // Modulates the activity of RHO-like proteins and connects extracellular signals to cytoskeletal activities. Acts as a GDPdissociation stimulator protein that stimulates the GDP-GTP exchange activity of RHO-like GTPases and activates them. Mediates extracellular laminin signals to activate Rac1, contributing to neurite growth. Involved in lamellipodial formation and advancement of the growth cone of embryonic hippocampal neurons. Promotes migration of neurons in the cerebral cortex.
# Subcellular location // Cytoplasm. Cell projection . lamellipodium. Cell projection . filopodium. Cell projection . growth cone. Note: Localizes to the plasma membrane in neurites.
# Tissue specificity // Expressed in the occipital, frontal and temporal lobes, cerebellum, putamen and testis.
# Sequence similarities // Belongs to the TIAM family. Contains 1 DH (DBL-homology) domain. Contains 1 PDZ (DHR) domain. Contains 2 PH domains. Contains 1 RBD (Ras-binding) domain.

Character

Type Polyclonal Antibody
Immunogen Recombinant protein of full length Human TIAM2
Raised in Mouse
Source Mouse Serum
Purification Protein A purified
Cross Reactivity Human, Rat
Concentration 0.45 mg/mL
Contents(Volume) 50 ug(200 ul / vial )
Label Unlabeled
Buffer PBS, pH 7.2
Storage Store at -20Ž long term, store at 4Ž short term. Avoid repeated freeze-thaw cycles.

<Reference>
1. Chiu C.-Y., et al. "Cloning and characterization of T-cell lymphoma invasion and metastasis 2 (TIAM2), a novel guanine nucleotide exchange factor related to TIAM1." Genomics 61:66-73(1999)
2. Bechtel S., et al. "The full-ORF clone resource of the German cDNA consortium." BMC Genomics 8:399-399(2007)
3. The MGC Project Team. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." Genome Res. 14:2121-2127(2004)

Product List

Product Name Cat# Quantity Price

Anti TIAM2, Human (Mouse) Unlabeled DataSheet

KAL-KB541

50 UG N/A

Product Name Cat# Quantity Price

Anti MOK, Mouse (Rabbit) Unlabeled DataSheet

KAL-KR085

25 UG ¥49,000
$654

Anti Usp11, Mouse (Rabbit) Unlabeled DataSheet

KAL-KG403

25 UG ¥49,000
$654

Anti CEACAM5, Human (Mouse) Unlabeled DataSheet

KAL-KB468

50 UG N/A

Anti TACSTD1, Human (Mouse) Unlabeled DataSheet

KAL-KB479

50 UG N/A

Anti MPL, Human (Mouse) Unlabeled DataSheet

KAL-KB480

50 UG N/A

Anti TIAM2, Human (Mouse) Unlabeled DataSheet

KAL-KB541

50 UG N/A

Anti DDX39, Human (Mouse) Unlabeled DataSheet

KAL-KC570

50 UG ¥55,000
$734

Anti GRHPR, Human (Mouse) Unlabeled DataSheet

KAL-KC595

50 UG ¥55,000
$734

Anti GRHPR, Human (Mouse) Unlabeled DataSheet

KAL-KC597

50 UG ¥55,000
$734

Anti AKR7A3, Human (Mouse) Unlabeled DataSheet

KAL-KC598

50 UG ¥55,000
$734

“Anti Human TIAM2 Polyclonal Antibody” also belongs to the following categories.