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Anti Human CD44 ICD (intracellular domain) Polyclonal Antibody


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Application

Recommended Antibody Dilutions
ELISA WB IHC ICC
Not Tested 15-20 100-150 100-150
IP FCM IF Neutralization
15-20 Not Tested 100-150 Not Tested

(μg/mL)


The data is provided from Division of Gene Regulation Institute for Advanced Medical Research School of Medicine, Keio Univ., Japan

 

<UniPlot Summary>
# Function Receptor for hyaluronic acid (HA). Mediates cell-cell and cell-matrix interactions through its affinity for HA, and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases (MMPs). Adhesion with HA plays an important role in cell migration, tumor growth and progression. Also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes. Great protein heterogeneity due to numerous alternative splicing and post-translational modification events.
# Subcellular location Membrane ; Single-pass type I membrane protein.
# Tissue specificity Isoform 10 (epithelial isoform) is expressed by cells of epithelium and highly expressed by carcinomas. Expression is repressed in neuroblastoma cells.
# /Sequence similarities Contains 1 Link domain.

Character

Type Polyclonal Antibody
Immunogen Partial peptide of Human CD44 (DQFMTADETRNLQNVDMKIGV)
Raised in Rabbit
Source Rabbit Serum
Purification Protein G purified
Cross Reactivity Human
Concentration 0.25 mg/mL
Contents (Volume) 200μg (800μL/vial)
Label Unlabeled
Buffer PBS [containing2% Block Ace as a stabilizer, 0.1% Proclin as a bacteriostat]
Storage Store below –20Ž. Once thawed, store at 4Ž. Repeated freeze-thaw cycles should be avoided.

<Reference>
1) Okamoto I, et al: Oncogene (1999) 18:1435-1446
2) Okamoto I, et al: J Biol Chem (1999) 36: 25525-25534
3) Kawano Y, et al: J Biol Chem (2000) 38: 29628-29635
4) Okamoto I, et al: J Cell Biol (2001) 155: 755-762
5) Murakami D, et al., Oncogene (2003) 22:1511-1516
6) Nagano O, et al., J Cell Biol (2004) 165: 893-902
7) Takahashi E, et al., J Biol Chem. (2010) 285: 4060-73.

Product List

Product Name Cat# Quantity Price

Anti CD44ICD, Human (Rabbit) Unlabeled DataSheet

KAL-KO601

200 UG ¥49,000
$654

Product Name Cat# Quantity Price

Anti CD44ICD, Human (Rabbit) Unlabeled DataSheet

KAL-KO601

200 UG ¥49,000
$654

Anti MOK, Mouse (Rabbit) Unlabeled DataSheet

KAL-KR085

25 UG ¥49,000
$654

Anti Usp11, Mouse (Rabbit) Unlabeled DataSheet

KAL-KG403

25 UG ¥49,000
$654

Anti DDX39, Human (Mouse) Unlabeled DataSheet

KAL-KC570

50 UG ¥55,000
$734

Anti GRHPR, Human (Mouse) Unlabeled DataSheet

KAL-KC595

50 UG ¥55,000
$734

Anti GRHPR, Human (Mouse) Unlabeled DataSheet

KAL-KC597

50 UG ¥55,000
$734

Anti AKR7A3, Human (Mouse) Unlabeled DataSheet

KAL-KC598

50 UG ¥55,000
$734

“Anti Human CD44 ICD (intracellular domain) Polyclonal Antibody ” also belongs to the following categories.