Anti Bovine NR5A1 Polyclonal Antibody


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Application

ELISA WB IHC ICC
1.0 1.0-5.0 1.0-2.0 1.0-5.0
IP FCM IF Neutralization
5.0-10 Not Tested
1.0-5.0 Not Tested

(μg/mL)

<UniPlot Summary>
Transcriptional activator. Seems to be essential for sexual differentiation and formation of the primary steroidogenic tissues. Binds to the Ad4 site found in the promoter region of steroidogenic P450 genes such as CYP11A, CYP11B and CYP21B. Also regulates the AMH/Muellerian inhibiting substance gene as well as the AHCH and STAR genes. 5'-YCAAGGYC-3' and 5'-RRAGGTCA-3' are the consensus sequences for the recognition by NR5A1. The SFPQ-NONO-NR5A1 complex binds to the CYP17 promoter and regulates basal and cAMP-dependent transcriptional avtivity. Binds phospholipids with a phosphatidylinositol (PI) headgroup, in particular PI(3,4)P2 and PI(3,4,5)P3.

Character

Type Polyclonal Antibody
Immunogen Recombinant protein of Bovine NR5A1 (full length)
Raised in Rabbit
Source Rabbit Serum
Purification Protein G purified
Cross Reactivity Mouse
Concentration 0.25 mg/mL
Contents (Volume) 50μg (200μL/vial)
Label Unlabeled
Buffer PBS [containing2% Block Ace as a stabilizer, 0.1% Proclin as a bacteriostat]
Storage Store below – 20Ž. Once thawed, store at 4Ž. Repeated freeze-thaw cycles should be avoided.

<Reference>
1) Nomura M, et al: J. Biochem(1998) 124F217-224 (Application Reference)

Product List

Product Name Cat# Quantity Price

Anti NR5A1, Bovine (Rabbit) Unlabeled DataSheet

KAL-KO611

50 UG ¥49,000
$654

To be used for research only. DO NOT use for human gene therapy or clinical diagnosis.



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