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Monoclonal Antibodies to Transcription Factors and Nuclear DNA Binding Proteins

Anti CBL [CBL2, C-CBL, RNF55] monoclonal antibody (clone : 2111C3a)


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Background

The cbl oncogene was first identified as part of a transforming retrovirus which induces mouse pre-B and pro-B cell lymphomas. As an adaptor protein for receptor protein-tyrosine kinases, it positively regulates receptor protein-tyrosine kinase ubiquitination in a manner dependent upon its variant SH2 and RING finger domains. Ubiquitination of receptor protein-tyrosine kinases terminates signaling by marking active receptors for degradation. [NCBI Entrez Gene Summary]

Application

[Western Blot]
Detection of human CBL by Western blot. Samples: Whole cell lysate (25 μg) from HT-1080 cells. [Lot No. 2111C3a-1]

Predicted molecular weight: 99 kDa

Western_blot_protocolPDF

Product List

Product Name Cat# Quantity Price

Anti CBL, Human (Mouse) Unlabeled DataSheet

CBX-CBX00443

100 UG ¥39,000
$520

“Anti CBL [CBL2, C-CBL, RNF55] monoclonal antibody (clone : 2111C3a)” also belongs to the following categories.