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Monoclonal Antibodies to Transcription Factors and Nuclear DNA Binding Proteins

Anti ESE-1 [ELF3 , ERT, ESX, EPR-1] monoclonal antibody (clone : ELF3B10C4)


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Background

Transcriptional activator that binds and transactivates ETS sequences containing the consensus nucleotide core sequence GGA[AT]. Acts synergistically with POU2F3 to transactivate the SPRR2A promoter and with RUNX1 to transactivate the ANGPT1 promoter. Also transactivates collagenase, CCL20, CLND7, FLG, KRT8, NOS2, PTGS2, SPRR2B, TGFBR2 and TGM3 promoters. Represses KRT4 promoter activity. Involved in mediating vascular inflammation. May play an important role in epithelial cell differentiation and tumorigenesis. May be a critical downstream effector of the ERBB2 signaling pathway. May be associated with mammary gland development and involution. Plays an important role in the regulation of transcription with TATA-less promoters in preimplantation embryos, which is essential in preimplantation development (By similarity){EC9, EC6, EC8, EC10, EC15, EC1, EC16, EC14, EC17, EC18, EC19, EC20, EC12, EC21, EC3, EC5, EC22, EC2, EC23, EC13, EC4}. [UniProtKB@Function]

Application

[Western Blot]
Western blot analysis of immunized recombinant protein, using anti-ELF3 monoclonal antibody.

Western_blot_protocolPDF

Product List

Product Name Cat# Quantity Price

Anti ELF3, Human (Mouse) Unlabeled DataSheet

CBX-CBX00272

100 UG ¥39,000
$520

“Anti ESE-1 [ELF3 , ERT, ESX, EPR-1] monoclonal antibody (clone : ELF3B10C4)” also belongs to the following categories.