• HOME
  • Products
  • Anti Pigment Epithelium-Derived Factor (PEDF) monoclonal antibody

useful in research for angionenesis and neuronal system

Anti Pigment Epithelium-Derived Factor (PEDF) monoclonal antibody


print

Background

Pigment Epithelium-Derived Factor ( PEDF ), a protein previously shown to have neurotrophic activity, is indispensable for neuronal development, differentiation and existence adjacent to retina.
The amount of inhibitory PEDF produced by retinal cells was positively correlated with oxygen concentrations,suggesting that its loss play a permissive role in ischemia-driven retinal neovascularization. So that, PEDF is likely to contribute to regulate of blood vessels growth in eye by creating a permissive environment for angiogenesis when oxygen is limiting and an inhibitory environment oxygen concentrations are normal or high ( Science Vol 285: 245-248,1999).
PEDF may be a therapeutic target pathologic ocular neovascularization as well as for retinoblastomas.
This antibody could detect PEDF with western-blotting method in medium of retinal pigment epithelium cell. This antibody is useful in research for angionenesis and neuronal system.

 

Package Size 50μg (200μL / vial)
Format Mouse monoclonal antibody 0.25 mg/mL
Buffer Block Ace as a stabilizer, containing 0.1%Proclin as bacteriostat
Storage Store below -20°C
Once thawed, store at 4°C. Repeated freeze-thaw cycles should be avoided.
Clone No.
Sub class
Purification method
14K
IgG1
The cell line was grown on non-serum medium, from which the antibody was purified by Protein G affinity chromatography.
Immunoreactivity for western-Blotting Optimum concentration:0.5 `1μg/mL

 

 

SampleFPEDF in the medium of retinal pigment epithelium

Primary antibodyF
a Control mouse IgG
b Anti PEDF monoclonal antibody

2 nd antibodyFa,bF HRP labeled anti mouse IgG

Product List

Product Name Cat# Quantity Price

Anti PEDF, Human (Mouse) Unlabeled DataSheet

KAL-KM037

50 UG ¥55,000
$734

To be used for research only. DO NOT use for human gene therapy or clinical diagnosis.


“Anti Pigment Epithelium-Derived Factor (PEDF) monoclonal antibody” also belongs to the following categories.