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Anti Organic Anion Transporter 3 (OAT3) Polyclonal Antibody


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Background

To eliminate the drug, xenobiotics, a varirety of endogeneous substances, and their metabolites out of the body, specific membrane proteins named transporters are required. There are two major pathways for the elimination, one of which is hepatic one through bile, and another is renal one to urine. The transporter fall into various transport systems by the transportative substrate. In particular, oraganic ion transporter family is comprised of organic anion transport family (OAT), oraganic cation transport family (OCT), OCTN/carnitine transport family, and OAT are multispecific organic anion transpoters, the substrates of which include a lot of both endogeneous and exogeneous anions.

Product List

Anti Human Organic Anion Transporter 3 (OAT3) Polyclonal Antibody

Human organic anion transporter 3 (OAT3) encodes a 543 amino acid residue protein, and which is predicted 12 putative membran-spanning protein. OAT3 is expressed in the kidney, brain, and skeletal muscle. OAT3 mediated the uptake of organic anions, such as PAH (ρ-aminohippurate), ochratoxin A and estrone sulfate, prostaglandin E2 (PGE2 ), and cimetidine. This has been proved to be useful for immunohistochemistry .

Package Size 25μg (250μL / vial)
Format Rabbit polyclonal antibody 0.1 mg/mL
Buffer Block Ace as a stabilizer, containing 0.1%Proclin as bacteriostat
Storage Store below -20°C Once thawed, store at 4°C. Repeated freeze-thaw cycles should be avoided.
Purification method This antibody was purified from rabbit serum immunized with synthesized C-end peptide of human OAT3 by peptide affinity chromatography.
Working dilution for immunohistochemistry 1-5μg/mL


Human Kidney (frozen section)


Product Name Cat# Quantity Price

Anti Organic Anion Transporter 3 / OAT3, Human (Rabbit) Unlabeled DataSheet

KAL-KE032

25 UG ¥49,000
$654

Anti Rat Organic Anion Transporter 3 (OAT3) Polyclonal Antibody

Rat organic anion transporter 3 (OAT3) encodes a 536 amino acid residue protein, of which molecular weight is 130kDa. OAT3 is expressed in the kidney, liver, brain, and eye. OAT3 mediated the uptake of organic anions, such as PAH (ƒÏ-aminohippurate), ochratoxin A and estrone sulfate, cimetidine, and prostaglandin E2. This antidody has been proved to be useful for immunohistochemistry.


Rat Kidney (frozen section)


Product Name Cat# Quantity Price

Anti Organic Anion Transporter 3 / OAT3, Rat (Rabbit) Unlabeled DataSheet

KAL-KE035

25 UG ¥49,000
$654

To be used for research only. DO NOT use for human gene therapy or clinical diagnosis.



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