useful for the research of the diabetic and Alzheimer's disease.

Anti Human RAGE Polyclonal Antibody


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Background

RAGE is the receptor of AGE, advanced glycation end products with 35,000 molecular weight and was cloned from bovine lung in 1992 ( David Stern et al.,). RAGE has been found in several tissues such as monocytes, macrophages, endothelial cells, astocytes. The ligand of RAGE is demonstrated not only AGE but also anfoterin, EN-RAGE, N-carboxymethyllysine(CML),β-amyloid and so on. The accumulation of AGE-proteins in vivo has been demonstrated in several disease, it is not clear whether AGE-proteins accumulated in vivo is a direct cause of the disease or rather reflects its effect. Regarding this issue, AGE-modified proteins are known to interact with several cells by the AGE-receptors and induce several cellular phenomena. Recently, it has been discovered that RAGE is involved in pathophysiological function of diabetes and Alzheimer’s disease. This antibody is affinity purified rabbit polyclonal antibody raised against partial peptide of human RAGE and should be used for western blotting or immunohistochmistry.

y AGE receptors z


 AGEs Antibody Flyer [PDF]
 AGEs Antibody Flyer@(print file) [PDF]

Western blotting Sample: Cell lysates of CHO-RAGE or A549 cells (5μg/lane)

Preparation of antibodies and instruction: Prof. S Horiuch., Department of Biochmistry Kumamoto University School of Medicine

Package Size 100μg(400μL / vial)
Format Rabbit polyclonal antibody ,0.25mg/mL
Buffer Block Ace as a stabilizer, containing 0.1% Proclin as a bacteriostat
Storage Below –20°C until needed
Purification method This antibody was purified from rabbit serum by Protein G ffinity chromatography.
Product List

Product Name Cat# Quantity Price

Anti RAGE, Human (Rabbit) Unlabeled DataSheet

KAL-KH039

100 UG ¥49,000
$654

“Anti Human RAGE Polyclonal Antibody” also belongs to the following categories.