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useful for the research of the function clarification of Aldehyde Oxidase and the influence on the condition.

Anti Rat Aldehyde Oxidase Polyclonal Antibody


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Background

Though similar in catalytic function structure and catalytic function, aldehyde oxidase displays higher@substrate specificity than xanthine oxidase. Recently, a role for AO in cell differentiation and proliferation involving retinol as AO substrate has been suggested. A role for AO in amyotrophic lateral sclerosis and ischemia/reperfusion failure as also been suggested, due to injury by superoxide produced by AO activity. However, the precise physiological roles of AO remain to be determined.

This antibody shows little cross reaction with xanthine oxidase and has been used to detect AO activity in rat liver. Further, the antibody was found to inhibit AO activity Thus, this antibody will be useful to clarify AO functions in cell and tissue physiology.

Application

western blotting : 0.5`2μg/mL

Character

Package Size 25μg (100μL / vial)
Format Rabbit polyclonal antibody 0.25mg/mL
Buffer PBS [containing 2% Block Ace as a stabilizer, 0.1% Proclin as a bacteriostat]
Storage Store below -20°C
Once thawed, store at 4°C. Repeated freeze-thaw cycles should be avoided.
Purification method This antibody was purified from rabbit serum immunized with Rat Aldehyde Oxidase purified from Rat liver by antigen affinity chromatography.

<Reference>
1. Beedham C. : Drug Metab Rev. 1985;16(1-2):119-56
2. Kisker C. et al. : Annu Rev Biochem. 1997;66:233-67
3. Wright RM. et al. : J Biol Chem. 1999 Feb 5;274(6):3878-86
4. Maia L. et al. : Arch Biochem Biophys. 2002 Apr 1;400(1):48-53
5.Beedham C. ‘Molybdenum Hydroxylases.’ In Enzyme Systems that Metabolise Drugs and Other Xenobiotics, Ioannides C. and John Wiley (ed.), New York, 2002, 147-87

Product List

Product Name Cat# Quantity Price

Anti Aldehyde Oxidase, Rat (Rabbit) Unlabeled DataSheet

KAL-KR063

25 UG ¥49,000
$654

Product Name Cat# Quantity Price

Anti CaM Kinase II Δ1/2/3/4, Rat (Rabbit) Unlabeled DataSheet

KAL-KY041

200 UG ¥49,000
$654

Anti Aldehyde Oxidase, Rat (Rabbit) Unlabeled DataSheet

KAL-KR063

25 UG ¥49,000
$654

Anti Adenosine Deaminase2, Chicken (Rabbit) Unlabeled DataSheet

KAL-KR081

25 UG ¥49,000
$654

Anti Indoleamine-2,3 dioxygenase / IDO, Mouse (Rabbit) Unlabeled DataSheet

KAL-KR101

150 UG ¥49,000
$654

Anti ATP1B3, Human (Mouse) Unlabeled DataSheet

KAL-KB465

50 UG N/A

Anti NEDD4L, Human (Mouse) Unlabeled DataSheet

KAL-KB521

50 UG N/A

Anti NUDT9, Human (Mouse) Unlabeled DataSheet

KAL-KB523

50 UG N/A

Anti ATP2C1, Human (Mouse) Unlabeled DataSheet

KAL-KB542

50 UG N/A

Anti PDCD8, Human (Mouse) Unlabeled DataSheet

KAL-KB543

50 UG N/A

Anti DDX11, Human (Mouse) Unlabeled DataSheet

KAL-KB545

50 UG N/A

Anti CYB5R3, Human (Mouse) Unlabeled DataSheet

KAL-KB547

50 UG N/A

Anti UQCRC2, Human (Mouse) Unlabeled DataSheet

KAL-KB556

50 UG N/A

Anti UQCRC1, Human (Mouse) Unlabeled DataSheet

KAL-KB557

50 UG N/A

Anti EME1, Human (Mouse) Unlabeled DataSheet

KAL-KB559

50 UG N/A

To be used for research only. DO NOT use for human gene therapy or clinical diagnosis.



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