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High-quality antibody necessary for transcriptional control signal

Anti human COUP-TF I mouse monoclonal antibody


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COUP-TF I : Chicken ovalbumin upstream promoter-transcription factor

Background

Chicken ovalbumin upstream promoter transcription factor I (COUP-TFI, EAR3, COUP-TFA; NR2F1) is a member of orphan nuclear receptor.COUP-TF I is expressed in specific regions of the rostral brain, in stripes in the presumptive hindbrain.COUP-TFI has varied roles in the development of the peripheral nervous system, such as early regionalization of the neocortex, differentiation of subplate neurons and guidance of thalamocortical axons.COUP-TFs were shown to interact with a number of other nuclear receptors.

Application

<Recommended Concentration>
In order to obtain the best results, optimal working dilutions should be determined by each individual user.
  Western Blot : 1 ug/mL
  ELISA : 0.1ug/mL
  Immunoprecipitation : Decide by use
  Mmunohistochemistry : 10-50 ug/mL


Human Prostate gland paraffin section

Rat Cerebrum paraffin section

<Reference>
1. Jae Mi Suh, et al. Mol Endocrinol, Dec. 2006, 20(12):34123420
2. Jun Qin, et al.Developmemtal Dynamics, 2007, 236:810-820

Specificity

This antibody specifically recognizes human COUPTF I and cross reacts with mouse and rat COUP-TF I.This antibody does not recognize human COUP-TF II and EAR2.

Product List

Product Name Cat# Quantity Price

Anti COUP-TF I, Human (Mouse)  DataSheet

PPX-PP-H8132-00

0.1 ML ¥50,000
$667

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