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High-quality antibody necessary for transcriptional control signal

Anti human COUP-TF II mouse monoclonal antibody


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COUP-TF II : Chicken ovalbumin upstream promoter-transcription factor II

Background

Chicken ovalbumin upstream promoter transcription factor II (COUP-TFII, ARP-1, COUP-TFB; NR2F2) is a member of orphan nuclear receptor. COUP-TFII is expressed in tongue, follicles of vibrissae, cochIea and in stroma of nasal septum. COUP-TFII has roles in angiogenesis, vascular remodeling and heart development. COUP-TFs were shown to interact with a number of other nuclear receptors.

Application

<Recommended Concentration>
In order to obtain the best results, optimal working dilutions should be determined by each individual user
  Western Blot : 1 ug/mL
  ELISA : 0.1 ug/mL
  Immunoprecipitation : Decide by use
  Supershift Assay : Not yet tested
  Chromatin immunoprecipitation : Not yet tested
  Immunohistochemistry: 10 ug/mL


Human Convoluted tubule paraffin section

Glomerular paraffin section

<Reference>
1. Lee CT, et al. Mol Cell Biol., 24(24): 10835-43, 2004.You LR, et al. Proc Natl Acad Sci U S A. 2005 Nov 8;102 (45):16351-6.
2. Jae Mi Suh, et al. Mol Endocrinol, Dec. 2006, 20(12): 3412-3420
3. Jun Qin, et al. Developmemtal Dynamics, 2007, 236: 810-820

Specificity

This antibody specifically recognizes human COUPTFII and cross reacts with mouse and rat COUP-TFII. This antibody does not recognize human COUPTFI and EAR2.

Product List

Product Name Cat# Quantity Price

Anti COUP-TF II, Human (Mouse)  DataSheet

PPX-PP-H7147-00

0.1 ML ¥50,000
$667

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